| 项目编号 |
PRJCA040056 |
| 项目标题 |
Comparative single-cell analyses identify shared and divergent features of human autoimmune diseases |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
|
| 描述信息 |
This study used integrative single-cell RNA sequencing to analyze immune cell profiles in six autoimmune diseases, uncovering disease- and cell type-specific transcriptional patterns. Key findings included the identification of gene clusters enriched in cytotoxic CD8+ T cells and myeloid cells, which are crucial for immune responses. The research provides valuable insights into autoimmune disease mechanisms and offers a resource for developing targeted therapies. |
| 样品范围 |
Single cell |
| 发布日期 |
2026-02-16 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
National Science Funds for Distinguished Young Scholars
|
T2125012
|
|
|
|
| 提交者 |
Kun
Qu (qukun@ustc.edu.cn)
|
| 提交单位 |
University of Science and Technology of China |
| 提交日期 |
2025-05-12 |
