| Accession |
PRJCA040084 |
| Title |
Metabolite profiling of mouse lung tumor tissue before and after immunotherapy |
| Relevance |
Medical |
| Data types |
Metabonomics
|
| Organisms |
Mus musculus
|
| Description |
To explore the impact of radiation pneumonitis on the efficacy of lung cancer immunotherapy, we performed immunotherapy on left lung tumor-bearing mice with or without radiation pneumonitis. Untargeted metabolomics was then used to detect and analyze metabolic characteristics of lung tumor tissue before and after treatment. The metabolomic data provided the basis for understanding how radiation pneumonitis affects lung cancer immunotherapy. |
| Sample scope |
Multiisolate |
| Release date |
2025-08-29 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 40777001
|
Immunotherapy enhances the risk of tumor oxidative stress and metastasis in lung cancer with radiation pneumonitis
|
Frontiers in Immunology
|
10.3389/fimmu.2025.1629170
|
2025
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
82202938
|
|
| National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
|
|
SZ2020ZD002
|
|
|
|
| Submitter |
Ruidi
Jiao (1281674197@qq.com)
|
| Organization |
National Cancer Center and National Clinical Research Center for Cancer and Cancer Hospital and Shenzhen Hospital |
| Submission date |
2025-05-13 |
