| 项目编号 |
PRJCA040084 |
| 项目标题 |
Metabolite profiling of mouse lung tumor tissue before and after immunotherapy |
| 涉及领域 |
Medical |
| 数据类型 |
Metabonomics
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
To explore the impact of radiation pneumonitis on the efficacy of lung cancer immunotherapy, we performed immunotherapy on left lung tumor-bearing mice with or without radiation pneumonitis. Untargeted metabolomics was then used to detect and analyze metabolic characteristics of lung tumor tissue before and after treatment. The metabolomic data provided the basis for understanding how radiation pneumonitis affects lung cancer immunotherapy. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-08-29 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40777001
|
Immunotherapy enhances the risk of tumor oxidative stress and metastasis in lung cancer with radiation pneumonitis
|
Frontiers in Immunology
|
10.3389/fimmu.2025.1629170
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82202938
|
|
| National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
|
|
SZ2020ZD002
|
|
|
|
| 提交者 |
Ruidi
Jiao (1281674197@qq.com)
|
| 提交单位 |
National Cancer Center and National Clinical Research Center for Cancer and Cancer Hospital and Shenzhen Hospital |
| 提交日期 |
2025-05-13 |
