| Accession |
PRJCA040090 |
| Title |
Single-cell transcriptomic data of eye organoids derived from wild-type and RAX2-KO hESCs |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
|
| Description |
To explore the influence of RAX2 on human retinal development, the CRISPR/Cas9 system was employed to disrupt critical exons of RAX2 in human embryonic stem cells (hESCs) line H9. WT and RAX2 knockout (RAX2-KO) hESCs were grown in 3D culture for 66 days (D66) using BMP4-induced Rentila Organoids (ROs) self-organization protocol, and twenty-four ROs were harvested for scRNA-seq from each of WT and RAX2-KO group. |
| Sample scope |
Multiisolate |
| Release date |
2026-02-26 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Beijing Natural Science Foundation
|
|
7242176
|
|
|
|
| Submitter |
Guang
Liu (liuguang@ibms.pumc.edu.cn)
|
| Organization |
Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College |
| Submission date |
2025-05-09 |
