| 项目编号 |
PRJCA040195 |
| 项目标题 |
Spatial Transcriptomics Defines the Molecular Progression, Invasion, and Immune Landscape of IPMN and IPMN-Derived Pancreatic Cancer |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are precursor lesions of pancreatic ductal adenocarcinoma (PDAC). A total of 117 spatial transcriptomic areas of interests (AOIs) from 12 IPMN and PDAC patients were analyzed to delineate spatially resolved expression-based intertumoral trajectories and intratumoral heterogeneity associated with distinct immune microenvironments. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-10-15 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 41381181
|
Spatial transcriptomics defines the molecular progression, invasion and immune landscape of IPMN and IPMN-derived pancreatic cancer
|
Gut
|
10.1136/gutjnl-2025-336117
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Chinese Academy of Sciences (CAS)
|
the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences
|
2024-12M-ZD-001
|
|
|
|
| 提交者 |
Ming
Cui (cuiming660@126.com)
|
| 提交单位 |
Peking Union Medical College Hospital |
| 提交日期 |
2025-05-14 |
