| 项目编号 |
PRJCA041438 |
| 项目标题 |
Screen potential marker proteins influencing spermatogenesis in the testes of Shandong Black Cattle bulls via multi-omics integrated analysis. |
| 涉及领域 |
Agricultural |
| 数据类型 |
Metabonomics
|
| 物种名称 |
Bos taurus
|
| 描述信息 |
This study was designed to identify candidate marker proteins that influence the growth and development of Shandong Black Cattle bull testes through a multi-omics joint analysis, thereby providing a certain theoretical basis for testis growth and development as well as bull selection. Eight 12-month-old Shandong Black Cattle bulls were selected, and testes tissues were collected. The testes were categorized into two groups based on their morphological characteristics: Group 1 (weight > 120 g) and Group 2 (weight < 120 g). Group 2 was employed as the control group to construct a protein and metabolite library for joint analysis to screen candidate marker proteins that affect testis growth and development. Metabolomics demonstrated that 59 upregulated metabolites were enriched in the glucose metabolism pathway (uridine diphosphate glucose), and 14 downregulated metabolites were significantly enriched in metabolic pathways (hypoxanthine). |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-06-10 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40596853
|
Identification of candidate proteins influencing spermatogenesis in Shandong black cattle via integrated multiomics analysis
|
BMC Genomics
|
10.1186/s12864-025-11825-1
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Shandong Province advantageous characteristic industrial Cluster construction project
|
|
NA
|
Shandong Province advantageous characteristic industrial Cluster construction project - Shandong Agricultural Industry Word (2021) No. 22.
|
|
|
| 提交者 |
YA JUAN
DONG (etcenter@126.com)
|
| 提交单位 |
Qingdao Agricultural University |
| 提交日期 |
2025-06-10 |
