| 项目编号 |
PRJCA041858 |
| 项目标题 |
RNA-seq analysis between KRAS-amplified and non-amplified colorectal cancer (CRC) tissue samples |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
This dataset contains differentially expressed genes (DEGs) identified by RNA-seq analysis between KRAS-amplified and non-amplified colorectal cancer (CRC) tissue samples. A total of eight CRC samples (n=4 per group) were analyzed to explore the transcriptional differences associated with KRAS copy number status. Gene expression was quantified and DEGs were identified using DESeq2. The table includes gene symbols, log2 fold changes, adjusted p-values, and expression levels. This dataset supports the investigation of KRAS amplification-related molecular changes in CRC. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-08-29 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40708044
|
KRAS amplification in colorectal cancer: correlations with clinicopathological features and prognosis in patients and prediction of response to targeted therapy
|
Journal of Translational Medicine
|
10.1186/s12967-025-06864-x
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Guangdong Basic and Applied Basic Research Foundation
|
|
2024A1515012875
|
RNA-seq analysis between KRAS-amplified and non-amplified colorectal cancer (CRC) tissue samples
|
|
|
| 提交者 |
Xuanhua
Yang (yangxh73@mail2.sysu.edu.cn)
|
| 提交单位 |
The Sixth Affiliated Hospital, Sun Yat-sen University |
| 提交日期 |
2025-06-18 |
