项目编号 PRJCA041977
项目标题 Fatty acid metabonomics analysis for BIU-87 cell line of TERC knockdown
涉及领域 Medical
数据类型 Metabonomics
物种名称 Homo sapiens
描述信息 Bladder cancer ranks second among the most prevalent malignancies of the urinary system. In recent years, long non-coding RNAs (lncRNAs) have been shown to regulate biological functions by interacting with proteins or other RNA molecules, thus playing crucial roles in tumor progression. In this study, we analyzed the association between lncRNA TERC and fatty acid metabolism through free fatty acid metabolomics in bladder cancer. We found that when TERC was knocked down in the bladder cancer cell line BIU-87, the contents of multiple unsaturated fatty acids in the cells were significantly downregulated. This indicates that TERC may regulate fatty acid metabolism in bladder cancer.
样品范围 Monoisolate
发布日期 2025-06-21
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
40759031 TERC Stimulates Fatty Acid Metabolism to Promote Bladder Cancer Progression Cancer Research 10.1158/0008-5472.CAN-24-3439 2025
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) General Program 82072362 The clinical value of NSCLC exosome lncRNA TERC and the mechanism of m6A modification to regulate the formation of neutrophil extracellular traps
提交者 Dong Li (lidong@tongji.edu.cn)
提交单位 Tongji University
提交日期 2025-06-20

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