| Accession |
PRJCA042535 |
| Title |
Energy Metabolic Reprogramming by PF40-Treated CD4T Cells Improves Insulin Resistance in BNL CL.2 Cells |
| Relevance |
Medical |
| Data types |
Metabonomics
|
| Organisms |
Mus
|
| Description |
CD4 T cells were isolated from PF40-treated T2DM rats and co-cultured with insulin-resistant BNL CL2 hepatocytes to investigate their regulatory effect on cellular insulin sensitivity. Using targeted energy metabolomics, the study profiled metabolic alterations in key energy pathways such as glycolysis and the TCA cycle. |
| Sample scope |
intestinal CD4 T cells |
| Release date |
2025-07-02 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 40937578
|
Intestinal CD4(+) T cells treated with Pseudostellaria heterophylla polysaccharide improve insulin resistance in BNL CL.2 cells by modulating PI3K/AKT signaling and energy metabolism
|
Molecular Medicine Reports
|
10.3892/mmr.2025.13682
|
2025
|
|
|
| Biomaterial provider |
Yongjun Kan |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| No funding support
|
|
|
|
|
|
| Submitter |
Yongjun
Kan (kyj@fjtcm.edu.cn)
|
| Organization |
Fujian Academy of Chinese Medical Sciences |
| Submission date |
2025-07-02 |
