| 项目编号 |
PRJCA043247 |
| 项目标题 |
Advanced HPSCC with TPF chemotherapy |
| 涉及领域 |
Medical |
| 数据类型 |
Raw sequence reads
Genome sequencing
Assembly
|
| 物种名称 |
|
| 描述信息 |
Hypopharyngeal squamous cell carcinoma (HPSCC), an aggressive head and neck cancer with dismal prognosis, faces persistent chemoresistance to standard TPF (docetaxel, cisplatin, 5-fluorouracil) regimen. However, the immunological mechanisms underlying chemoresistance remain undefined. Here, we performed longitudinal single-cell RNA sequencing (scRNA-seq) profiling of paired pre-/post-TPF HPSCC specimens, mapping immune cell dynamics underlying chemoresistance. |
| 样品范围 |
Single cell |
| 发布日期 |
2025-12-17 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82073009
|
|
|
|
| 提交者 |
Guo
Li (liguoent@csu.edu.cn)
|
| 提交单位 |
Department of Otolaryngology Head and Neck Surgery |
| 提交日期 |
2025-07-15 |
