| 项目编号 |
PRJCA044096 |
| 项目标题 |
Preoperative pembrolizumab combined with chemoradiotherapy for esophageal squamous cell carcinoma |
| 涉及领域 |
Medical |
| 数据类型 |
Single cell sequencing
|
| 物种名称 |
|
| 描述信息 |
This dataset contains raw single-cell RNA sequencing (scRNA-seq) data from tumor specimens of patients with locally advanced, resectable esophageal squamous cell carcinoma (ESCC) enrolled in a multicenter phase 1/2 trial of preoperative pembrolizumab plus chemoradiotherapy (PPCT) followed by surgery. To study tumor microenvironment remodeling, we performed scRNA-seq on 11 post-PPCT, 9 post-chemoradiotherapy (nCRT), and 8 treatment-naive (BS) tumor samples. |
| 样品范围 |
Single cell |
| 发布日期 |
2025-08-01 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82072557
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82372855
|
|
|
|
| 提交者 |
Hecheng
Li (lihecheng2000@hotmail.com)
|
| 提交单位 |
Ruijin Hospital, Shanghai jiaotong University School of Medicine |
| 提交日期 |
2025-08-01 |
