| 项目编号 |
PRJCA045183 |
| 项目标题 |
Role of IL-24 in airway inflammatory diseases |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Single cell sequencing
|
| 物种名称 |
Mus musculus
Homo sapiens
|
| 描述信息 |
Allergic rhinitis (AR) is a prevalent inflammatory disorder of the upper airways, driven by dysregulated type 2 immunity and epithelial cell dysfunction. Although the pathophysiology of AR has been extensively studied, the mechanisms underlying negative regulation of allergic responses remain poorly understood. Reportedly, IL24 modulates immune responses by affecting a variety of cells in lower respiratory disease. How IL24 affects the immune microenvironment in the upper respiratory tract is also worth studying. In this study, we used a combination of technique including scRNA seq and bulk RNA-seq to reveal the role of IL24 in chronic airway inflammatory diseases. |
| 样品范围 |
Single cell |
| 发布日期 |
2025-08-25 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
N/A
|
|
|
|
| 提交者 |
Yin
Yao (dr.yaoyin@hotmail.com)
|
| 提交单位 |
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology |
| 提交日期 |
2025-08-25 |
