| 项目编号 |
PRJCA048007 |
| 项目标题 |
Screening of TNK2 downstream phosphorylated proteins and interacting proteins |
| 涉及领域 |
Medical |
| 数据类型 |
Proteome
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
To identify phosphorylated proteins downstream of the non-receptor tyrosine kinase TNK2 and proteins that interact with TNK2, we first established control cells (vector) and Flag-TNK2 stably overexpressing cell lines in the mouse pancreatic cancer cell line KPC. Proteins were isolated and extracted, and differentially phosphorylated proteins were detected by phosphoprotein profiling. Second, IP experiments were performed in Flag-TNK2-overexpressing cells using a Flag antibody, and potential target proteins interacting with TNK2 were identified by protein profiling. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2025-10-13 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 41350522
|
immunosuppressive tumor microenvironment and synergizes with immunochemotherapy in pancreatic cancer
|
Nature Communications
|
10.1038/s41467-025-67197-3
|
2025
|
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| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| No funding support
|
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|
|
|
|
| 提交者 |
Chao
Wu (chaowutjmuch@163.com)
|
| 提交单位 |
Tianjin Medical University Cancer Institute and Hospital |
| 提交日期 |
2025-10-13 |
