| 项目编号 | PRJCA049462 | ||||||||||||||||
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| 项目标题 | Transcriptomic characterization of LRRC15+ cancer associated fibroblasts in human and mouse tumors via bulk and single-cell RNA sequencing | ||||||||||||||||
| 涉及领域 | Medical | ||||||||||||||||
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads Single cell sequencing |
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| 物种名称 |
Mus musculus
Homo sapiens |
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| 描述信息 | Cancer-associated fibroblasts (CAFs) are a critical and heterogeneous component of the tumor microenvironment, playing diverse roles in tumor progression. Here, we identify LRRC15+ CAFs as a tumor-specific CAF subset in lung cancer and propose LRRC15 as a potential therapeutic target. We provide a valuable resource for understanding the the phenotype, function, and conservation of LRRC15+ CAFs across human and mouse systems. | ||||||||||||||||
| 样品范围 | Multispecies | ||||||||||||||||
| 发布日期 | 2025-10-29 | ||||||||||||||||
| 项目资金来源 |
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| 提交者 | Zemin Zhang (zemin@pku.edu.cn) | ||||||||||||||||
| 提交单位 | Peking University | ||||||||||||||||
| 提交日期 | 2025-10-28 |