项目编号

PRJCA050765

项目标题

MHC class II genes influence the gut microbiota of wild golden snub-nosed monkeys

涉及领域

Evolution

数据类型

16S rRNA

物种名称

描述信息

Gut microbiota play a critical role in host health and nutrition and are regulated by both non-genetic factors and genetic variation. Although researchers studying mammalian feeding ecology have focused principally on non-genetic influences of gut microbiome composition, there is growing awareness of the important role that genes coding for the major histocompatibility complex (MHC) play in enabling the host immune system to distinguish between beneficial and pathogenic microbes. we examined MHC genes DRB1, DRB2, DQA1 and DQB1 along with 20 neutral microsatellites to test the relationship between host genetic variation and gut microbiota in a population of wild golden snub-nosed monkeys. Our research indicates that the MHC selectively shapes the gut microbiota by targeting specific taxa present in the gut rather than by regulating the entire composition of the gut microbial community.

样品范围

Multispecies

发布日期

2026-03-11

项目资金来源

机构	项目类型	授权项目ID	授权项目名称
National Natural Science Foundation of China (NSFC)		32371563
National Natural Science Foundation of China (NSFC)		32571756
National Natural Science Foundation of China (NSFC)		32071495
Ministry of Science and Technology of the People's Republic of China (MOST)		2024YFF1307300
Shaanxi Fundamental Science Research Project for Chemistry and Biology		23JHQ027

提交者

Jibing Yan (yjibingbing@163.com)

提交单位

Northwest University

提交日期

2025-11-10

项目包含数据信息

资源名称	描述
BioSample (164) show	-
SAMC6114302	YY_sum.fastq.gz_F_filt.fastq.gz
SAMC6114301	YY_spr.fastq.gz_F_filt.fastq.gz
SAMC6114300	YY_aut.fastq.gz_F_filt.fastq.gz
SAMC6114299	YQ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114298	YQ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114297	YL_sum.fastq.gz_F_filt.fastq.gz
SAMC6114296	YL_spr.fastq.gz_F_filt.fastq.gz
SAMC6114295	YL_aut.fastq.gz_F_filt.fastq.gz
SAMC6114294	YKY_sum.fastq.gz_F_filt.fastq.gz
SAMC6114293	YKY_spr.fastq.gz_F_filt.fastq.gz
SAMC6114292	YKY_aut.fastq.gz_F_filt.fastq.gz
SAMC6114291	YK_sum.fastq.gz_F_filt.fastq.gz
SAMC6114290	YK_spr.fastq.gz_F_filt.fastq.gz
SAMC6114289	YK_aut.fastq.gz_F_filt.fastq.gz
SAMC6114288	YG_sum.fastq.gz_F_filt.fastq.gz
SAMC6114287	YG_spr.fastq.gz_F_filt.fastq.gz
SAMC6114286	YG_aut.fastq.gz_F_filt.fastq.gz
SAMC6114285	YDD_aut.fastq.gz_F_filt.fastq.gz
SAMC6114284	YD_sum.fastq.gz_F_filt.fastq.gz
SAMC6114283	YD_spr.fastq.gz_F_filt.fastq.gz
SAMC6114282	YD_aut.fastq.gz_F_filt.fastq.gz
SAMC6114281	YC_sum.fastq.gz_F_filt.fastq.gz
SAMC6114280	YC_spr.fastq.gz_F_filt.fastq.gz
SAMC6114279	YC_aut.fastq.gz_F_filt.fastq.gz
SAMC6114278	YB_sum.fastq.gz_F_filt.fastq.gz
SAMC6114277	YB_spr.fastq.gz_F_filt.fastq.gz
SAMC6114276	YB_aut.fastq.gz_F_filt.fastq.gz
SAMC6114275	XZ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114274	XYD_sum.fastq.gz_F_filt.fastq.gz
SAMC6114273	XYD_spr.fastq.gz_F_filt.fastq.gz
SAMC6114272	XYD_aut.fastq.gz_F_filt.fastq.gz
SAMC6114271	XXQ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114270	XQ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114269	XL_sum.fastq.gz_F_filt.fastq.gz
SAMC6114268	XL_spr.fastq.gz_F_filt.fastq.gz
SAMC6114267	XL_aut.fastq.gz_F_filt.fastq.gz
SAMC6114266	XJJ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114265	XJJ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114264	XJJ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114263	XJ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114262	XJ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114261	XJ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114260	XH_sum.fastq.gz_F_filt.fastq.gz
SAMC6114259	XH_spr.fastq.gz_F_filt.fastq.gz
SAMC6114258	XH_aut.fastq.gz_F_filt.fastq.gz
SAMC6114257	XFZ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114256	XFZ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114255	XFZ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114254	XF_aut.fastq.gz_F_filt.fastq.gz
SAMC6114253	WX_sum.fastq.gz_F_filt.fastq.gz
SAMC6114252	WX_spr.fastq.gz_F_filt.fastq.gz
SAMC6114251	WX_aut.fastq.gz_F_filt.fastq.gz
SAMC6114250	WW_spr.fastq.gz_F_filt.fastq.gz
SAMC6114249	WW_aut.fastq.gz_F_filt.fastq.gz
SAMC6114248	TY_sum.fastq.gz_F_filt.fastq.gz
SAMC6114247	TY_spr.fastq.gz_F_filt.fastq.gz
SAMC6114246	TT_sum.fastq.gz_F_filt.fastq.gz
SAMC6114245	TT_spr.fastq.gz_F_filt.fastq.gz
SAMC6114244	TT_aut.fastq.gz_F_filt.fastq.gz
SAMC6114243	TS_aut.fastq.gz_F_filt.fastq.gz
SAMC6114242	TBG_spr.fastq.gz_F_filt.fastq.gz
SAMC6114241	TBG_aut.fastq.gz_F_filt.fastq.gz
SAMC6114240	SZ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114239	SZ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114238	SZ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114237	SX_spr.fastq.gz_F_filt.fastq.gz
SAMC6114236	QY_sum.fastq.gz_F_filt.fastq.gz
SAMC6114235	QY_spr.fastq.gz_F_filt.fastq.gz
SAMC6114234	QY_aut.fastq.gz_F_filt.fastq.gz
SAMC6114233	QQ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114232	QQ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114231	QQ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114230	QB_sum.fastq.gz_F_filt.fastq.gz
SAMC6114229	QB_spr.fastq.gz_F_filt.fastq.gz
SAMC6114228	QB_aut.fastq.gz_F_filt.fastq.gz
SAMC6114227	PPZ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114226	PPZ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114225	PPZ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114224	PP_sum.fastq.gz_F_filt.fastq.gz
SAMC6114223	PP_aut.fastq.gz_F_filt.fastq.gz
SAMC6114222	OP_sum.fastq.gz_F_filt.fastq.gz
SAMC6114221	OP_spr.fastq.gz_F_filt.fastq.gz
SAMC6114220	OP_aut.fastq.gz_F_filt.fastq.gz
SAMC6114219	NN_sum.fastq.gz_F_filt.fastq.gz
SAMC6114218	MM_spr.fastq.gz_F_filt.fastq.gz
SAMC6114217	MB_sum.fastq.gz_F_filt.fastq.gz
SAMC6114216	MB_spr.fastq.gz_F_filt.fastq.gz
SAMC6114215	MB_aut.fastq.gz_F_filt.fastq.gz
SAMC6114214	LS_sum.fastq.gz_F_filt.fastq.gz
SAMC6114213	LS_spr.fastq.gz_F_filt.fastq.gz
SAMC6114212	LS_aut.fastq.gz_F_filt.fastq.gz
SAMC6114211	LN_sum.fastq.gz_F_filt.fastq.gz
SAMC6114210	LN_spr.fastq.gz_F_filt.fastq.gz
SAMC6114209	LN_aut.fastq.gz_F_filt.fastq.gz
SAMC6114208	LJH_sum.fastq.gz_F_filt.fastq.gz
SAMC6114207	KL_sum.fastq.gz_F_filt.fastq.gz
SAMC6114206	KL_spr.fastq.gz_F_filt.fastq.gz
SAMC6114205	KL_aut.fastq.gz_F_filt.fastq.gz
SAMC6114204	KH_sum.fastq.gz_F_filt.fastq.gz
SAMC6114203	KH_spr.fastq.gz_F_filt.fastq.gz
SAMC6114202	KH_aut.fastq.gz_F_filt.fastq.gz
SAMC6114201	KD_sum.fastq.gz_F_filt.fastq.gz
SAMC6114200	KD_spr.fastq.gz_F_filt.fastq.gz
SAMC6114199	KD_aut.fastq.gz_F_filt.fastq.gz
SAMC6114198	JJ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114197	JJ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114196	JJ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114195	JH_aut.fastq.gz_F_filt.fastq.gz
SAMC6114194	HT_sum.fastq.gz_F_filt.fastq.gz
SAMC6114193	HT_spr.fastq.gz_F_filt.fastq.gz
SAMC6114192	HT_aut.fastq.gz_F_filt.fastq.gz
SAMC6114191	HH_sum.fastq.gz_F_filt.fastq.gz
SAMC6114190	HH_spr.fastq.gz_F_filt.fastq.gz
SAMC6114189	HH_aut.fastq.gz_F_filt.fastq.gz
SAMC6114188	HD_spr.fastq.gz_F_filt.fastq.gz
SAMC6114187	FY_sum.fastq.gz_F_filt.fastq.gz
SAMC6114186	FY_spr.fastq.gz_F_filt.fastq.gz
SAMC6114185	FY_aut.fastq.gz_F_filt.fastq.gz
SAMC6114184	FXQ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114183	FXQ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114182	FXQ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114181	FBZ_sum.fastq.gz_F_filt.fastq.gz
SAMC6114180	FBZ_spr.fastq.gz_F_filt.fastq.gz
SAMC6114179	FBZ_aut.fastq.gz_F_filt.fastq.gz
SAMC6114178	FBB_sum.fastq.gz_F_filt.fastq.gz
SAMC6114177	FBB_spr.fastq.gz_F_filt.fastq.gz
SAMC6114176	FBB_aut.fastq.gz_F_filt.fastq.gz
SAMC6114175	EX_sum.fastq.gz_F_filt.fastq.gz
SAMC6114174	EX_spr.fastq.gz_F_filt.fastq.gz
SAMC6114173	EX_aut.fastq.gz_F_filt.fastq.gz
SAMC6114172	ET_sum.fastq.gz_F_filt.fastq.gz
SAMC6114171	ET_spr.fastq.gz_F_filt.fastq.gz
SAMC6114170	ET_aut.fastq.gz_F_filt.fastq.gz
SAMC6114169	DYD_sum.fastq.gz_F_filt.fastq.gz
SAMC6114168	DYD_spr.fastq.gz_F_filt.fastq.gz
SAMC6114167	DYD_aut.fastq.gz_F_filt.fastq.gz
SAMC6114166	DX_sum.fastq.gz_F_filt.fastq.gz
SAMC6114165	DX_spr.fastq.gz_F_filt.fastq.gz
SAMC6114164	DX_aut.fastq.gz_F_filt.fastq.gz
SAMC6114163	DW_spr.fastq.gz_F_filt.fastq.gz
SAMC6114162	DW_aut.fastq.gz_F_filt.fastq.gz
SAMC6114161	DT_sum.fastq.gz_F_filt.fastq.gz
SAMC6114160	DT_spr.fastq.gz_F_filt.fastq.gz
SAMC6114159	DT_aut.fastq.gz_F_filt.fastq.gz
SAMC6114158	DD_sum.fastq.gz_F_filt.fastq.gz
SAMC6114157	DD_spr.fastq.gz_F_filt.fastq.gz
SAMC6114156	DD_aut.fastq.gz_F_filt.fastq.gz
SAMC6114155	DB_aut.fastq.gz_F_filt.fastq.gz
SAMC6114154	CB_sum.fastq.gz_F_filt.fastq.gz
SAMC6114153	CB_spr.fastq.gz_F_filt.fastq.gz
SAMC6114152	CB_aut.fastq.gz_F_filt.fastq.gz
SAMC6114151	BX_sum.fastq.gz_F_filt.fastq.gz
SAMC6114150	BX_spr.fastq.gz_F_filt.fastq.gz
SAMC6114149	BX_aut.fastq.gz_F_filt.fastq.gz
SAMC6114148	BTL_sum.fastq.gz_F_filt.fastq.gz
SAMC6114147	BTL_spr.fastq.gz_F_filt.fastq.gz
SAMC6114146	BTL_aut.fastq.gz_F_filt.fastq.gz
SAMC6114145	BT_sum.fastq.gz_F_filt.fastq.gz
SAMC6114144	BT_spr.fastq.gz_F_filt.fastq.gz
SAMC6114143	BT_aut.fastq.gz_F_filt.fastq.gz
SAMC6114142	BM_sum.fastq.gz_F_filt.fastq.gz
SAMC6114141	BM_spr.fastq.gz_F_filt.fastq.gz
SAMC6114140	BM_aut.fastq.gz_F_filt.fastq.gz
SAMC6114139	BC_spr.fastq.gz_F_filt.fastq.gz