| 项目编号 |
PRJCA051793 |
| 项目标题 |
No target metabolism serum |
| 涉及领域 |
Medical |
| 数据类型 |
Metabonomics
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
Emerging evidence demonstrates that chronic stress alters immunological, neurochemical and endocrinological functions, thereby promoting tumor progression. However, the underlying metabolic mechanism of chronic stress in tumor progression is still elusive. Using multi-omics analysis, we found that aminopeptidase N (ANPEP) was upregulated in tumors with chronic restraint, associating with the reprogramming of amino acid metabolism. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2025-11-21 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 41329521
|
Chronic stress–induced ANPEP drives liver cancer progression by increasing glutathione synthesis and inhibiting ferroptosis
|
The Journal of Clinical Investigation
|
10.1172/JCI195685
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
NA
|
|
|
|
| 提交者 |
Yongkang
Wu (418021579@qq.com)
|
| 提交单位 |
School of Basic Medical Sciences |
| 提交日期 |
2025-11-21 |
