| 项目编号 |
PRJCA054876 |
| 项目标题 |
Algal Blooms Drive Plasmid-Mediated ARG Conjugation in Eutrophic Lakes |
| 涉及领域 |
Environmental |
| 数据类型 |
Metagenome
Metatranscriptome
|
| 物种名称 |
|
| 描述信息 |
The primary objective of this study is to decouple the 'abundance' of antibiotic resistance genes (ARGs) from their 'mobility'. Using an integrated framework combining field observations, microcosm simulations, and metatranscriptomics, we aimed to elucidate how algal blooms promote the translocation of ARGs from chromosomal loci to mobile plasmids and facilitate their dissemination. Samples were collected from Chaohu Lake between April and August 2021 and sequenced using both Nanopore and Illumina platforms. In addition, 11 species of epiphytic bacteria were isolated from Chaohu Lake and co-cultured with Microcystis aeruginosa for further experiments, followed by metatranscriptomic sequencing. |
| 样品范围 |
Environment |
| 发布日期 |
2025-12-30 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
41977312
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
42477418
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
52322002
|
|
| Anhui Provincial Natural Science Foundation
|
|
2508085JX006
|
|
|
|
| 提交者 |
chaonan
wang (yuelang20130515@qq.com)
|
| 提交单位 |
Peking University |
| 提交日期 |
2025-12-30 |
