| 项目编号 |
PRJCA056813 |
| 项目标题 |
Accuracy of nanopore-based targeted next generation sequencing assay for detection of Mycobacterium tuberculosis and drug resistance from non-sputum specimens: a multicentre prospective study in China |
| 涉及领域 |
Medical |
| 数据类型 |
Targeted Locus (Loci)
Variation
Raw sequence reads
|
| 物种名称 |
|
| 描述信息 |
In this multicentre prospective lab-developed assay, 701 participants from five designated TB hospitals from different provinces in China were recruited. Non-sputum specimens were collected for tNGS, Xpert MTB/RIF (Xpert), and culture tests. The diagnostic accuracy of tNGS for TB patients was evaluated compared with microbiological reference standard (MRS). Phenotypic drug susceptibility tests (DSTs) were conducted using culture positive isolates and employed to assess the accuracy of tNGS for detecting drug resistance. |
| 样品范围 |
Multispecies |
| 发布日期 |
2026-01-26 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2022YFC2305003
|
|
|
|
| 提交者 |
Yu
Pang (pangyupound@163.com)
|
| 提交单位 |
Beijing Chest Hospital, Capital Medical University |
| 提交日期 |
2026-01-26 |
