项目编号 PRJNA1145302
项目标题 Genetic history of Scythia
涉及领域 Paleogenetics
数据类型 Genome sequencing
样品范围 Multiisolate
生物名称 Homo sapiens [Taxonomy ID: 9606]
描述信息 Great Scythia was the ancient Greek name for the area stretching from the northern Black Sea coast to the Middle Don. Using high-quality genomic data generated from 131 ancient individuals from Great Scythia and neighboring regions of the Bronze Age and the Iron Age, we established the genetic structure of the Scythians, revealing their diverse origin with major European Bronze Age ancestral components, and genetic traces of migration and invasions. We uncovered relationships between Scythians, including elite Scythians. Substantial endogamy in the Scythian clan was found. We examined Scythians' phenotypes and medical-genetic background and discovered a harmful gene mutation causing fructose intolerance. This ancient "Scythian" mutation has spread throughout West Eurasia and has become the most prevalent genetic cause of fructose intolerance in contemporary European populations.
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
40700493 Genetic history of Scythia. Science advances 2025
发布日期 2024-08-07
提交单位 Center for Genetics and Life Science, Sirius University of Science and Technology
数据来源 NCBI

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