Accession	PRJNA945578
Title	Tandem mobilization of anti-phage defenses alongside SCCmec cassettes
Relevance	Basic research and medical relevance
Data types	Raw sequence reads
Sample scope	Multispecies
Description	This study seeks to characterize the anti-phage defenses in staphylococci. Recent years have witnessed an explosion of new anti-phage defenses that have been functionally characterized in a few model organisms, but the defenses in clinically-relevant bacteria such as staphylococci have not been systematically explored. This study seeks to inventory the defenses in staphylococci, specifically those enriched within/near SCCmec cassettes, mobile genetic elements that are notorious for spreading antibiotic resistance. This work will help to inform the development of more effective phage-based therapeutics.
Organization	University of Illinois at Urbana-Champaign
Data Source	NCBI

Project Data

Resource name	Description
Experiment (14) show	-
SRX19696045	Illumina reads of SCCmec S. epidermidis RP62a delta cassette isolate 3
SRX19696048	Illumina reads of SCCmec circle junction of S. epidermidis RP62a
SRX19696046	Illumina reads of SCCmec S. epidermidis RP62a delta cassette isolate 2
SRX19696050	Illumina reads of CRISPR circle junction of S. epidermidis RP62a
SRX19696051	Illumina reads of excision junction of S. epidermidis RP62a
SRX19696044	Illumina reads of SCCmec S. epidermidis RP62a ancestral strain
SRX19696049	Illumina reads of Nhi-RM circle junction of S. epidermidis RP62a
SRX19696047	Illumina reads of SCCmec S. epidermidis RP62a delta cassette isolate 1
SRX24178213	Illumina reads of DNA released from S. epidermidis RP62A following challenge with phage Andhra
SRX24178212	Illumina reads of DNA released from S. epidermidis RP62A following challenge with phage Andhra
SRX24178216	Illumina reads of DNA released from S. epidermidis RP62A following challenge with phage Andhra
SRX24178214	Illumina reads of DNA released from S. epidermidis RP62A following challenge with phage Andhra
SRX24178217	Illumina reads of DNA released from S. epidermidis RP62A following challenge with phage Andhra
SRX24178215	Illumina reads of DNA released from S. epidermidis RP62A following challenge with phage Andhra