| 样本编号 | SAMC2114272 |
|---|---|
| 外部数据库编号 | GSA-Human: HRS506721 |
| 样品名称 | scRNA-P03_pre |
| 样本标题 | Pre-treatment-3 |
| 样品类型 | Human sample |
| 物种名称 | Homo sapiens |
| 描述信息 | Neoadjuvant chemotherapy (NAC) is the standard presurgery treatment for HR+ breast cancer (HR+ BC), but its response rate is frequently unsatisfactory, and the mechanism of chemoresistance and how NAC reshapes the immune microenvironment are still poorly understood. To investigate this question, the transcriptomes and spatial distribution patterns of cancer cells and immune cells from paired HR+ BC samples pre- and post-NAC were characterized with single-cell RNA sequencing |
| 样本属性 | *该样本包含更多受控访问信息，请通过GSA-Human系统申请项目HRA003664数据获取。 |
| 发布日期 | 2024-05-11 |
| 项目编号 | PRJCA009524 |
| 提交者 | Chao Ni (davenc@163.com) |
| 提交单位 | The Second Affiliated Hospital, Zhejiang University School of Medicine |
| 提交日期 | 2023-06-18 |
| 资源名称 | 描述 |
|---|---|
| GSA-Human (1) | - |
| HRA003664 (Controlled Access) | The transcriptomes and spatial distribution patterns of cancer cells and immune cells from paired HR+ BC samples pre- and post-NAC were characterized with single-cell RNA sequencing (N=8) and multiplexed immunofluorescence staining (N=21). |