样本编号	SAMC2157606
外部数据库编号	GSA-Human: HRS392323
样品名称	XGY_P_P05_P
样本标题	scRNA-seq of NSCLC before ICB + chemotherapy
样品类型	Human sample
物种名称	Homo sapiens
描述信息	Singleron single-cell RNA sequencing of NSCLC before neoadjuvant immunotherapy
样本属性	*该样本包含更多受控访问信息，请通过GSA-Human系统申请项目HRA002509数据获取。
发布日期	2024-06-09
项目编号	PRJCA009862
提交者	Peng Zhang (zhangpeng1121@tongji.edu.cn)
提交单位	Shanghai Pulmonary Hospital Tongji University
提交日期	2023-06-18

样本包含数据信息

资源名称	描述
GSA-Human (1)	-
HRA002509 (Controlled Access)	PD-(L)1 immune checkpoint inhibitors have shifted the treatment paradigm of advanced non-small cell lung cancer (NSCLC). Here, we combined single cell and spatial transcriptomics to identify the spatial landscape of the NSCLC tumor microenvironment (TME) during immunotherapy. Multidimensional bioinformatics analyses revealed distinct spatial compartmentalization of the TME. Our study provides novel insights into the complex spatiotemporal ecosystem of NSCLC and offers clues for combinational therapies.

资源名称

描述

GSA-Human (1)

HRA002509 (Controlled Access)

PD-(L)1 immune checkpoint inhibitors have shifted the treatment paradigm of advanced non-small cell lung cancer (NSCLC). Here, we combined single cell and spatial transcriptomics to identify the spatial landscape of the NSCLC tumor microenvironment (TME) during immunotherapy. Multidimensional bioinformatics analyses revealed distinct spatial compartmentalization of the TME. Our study provides novel insights into the complex spatiotemporal ecosystem of NSCLC and offers clues for combinational therapies.