| 样本编号 | SAMC3543905 |
|---|---|
| 外部数据库编号 | GSA-Human: HRS1221041 |
| 样品名称 | KO DFC organoid_d80 |
| 样本标题 | KO DFC organoid |
| 样品类型 | Human sample |
| 物种名称 | Homo sapiens |
| 描述信息 | Human iPS was knocked out of a human specific CTCF site in DLGAP1 gene, which was cultured into dosal forebrain cortex organoids to explore the role of the human sepecific CTCF site in the regulation of neuron function and differentiation |
| 样本属性 | *该样本包含更多受控访问信息,请通过GSA-Human系统申请项目HRA007191数据获取。 |
| 发布日期 | 2024-12-11 |
| 项目编号 | PRJCA020156 |
| 提交者 | zhonghui tang (tangzhh99@mail.sysu.edu.cn) |
| 提交单位 | Sun Yat-sen University |
| 提交日期 | 2024-04-21 |
| 资源名称 | 描述 |
|---|---|
| GSA-Human (1) | - |
| HRA007191 (Controlled Access) | Multi-omic datasets were generated from B lymphoblastoid cell lines, primary neuronal cells, and dorsal forebrain cortex organoids by using ChIA-PET, ChIP-seq, CUT&Tag, RNA-seq, scRNA-seq, and TSS-seq. Integrating with corresponding data from non-human primates (chimpanzee, gorilla, and macaque), this study explored the function and mechanism of the human-specific CTCF binding sites in forging human-specific gene expression patterns and phenotypic traits. |