| HRA010055
(Controlled Access)
|
This project aims to identify novel gene mutations in sporadic hypertrophic cardiomyopathy (HCM), particularly in patients with unexplained cases. We performed whole exome sequencing (WES) on HCM patients from Fuwai Hospital and Xi'an Jiaotong University First Affiliated Hospital to explore potential pathogenic variants. Patients selected for the study have left ventricular outflow tract obstruction and no family history of HCM. The project seeks to provide insights into early diagnosis, personalized treatment, and better clinical management of HCM through genetic analysis. |
