CIRIonco

circRNA Oncology Source

circRNA oncology source (CIRIonce) is an online platform built upon 2,535 curated RNA-seq datasets derived from human cancer and normal tissue samples, covering 30 cancer types. It hosts over 470,000 human cancer-related circular RNAs (circRNAs), with each circRNA accompanied by detailed annotations. Additionally, CIRIonco contains hierarchical circRNA biomarkers with the capability to distinguish among different biological systems, tissues, and diseases.

Prediction

Predict Tumor or Normal sample using circRNA BSJ ratios
based on the pretrained model

Drag & drop or click to upload a .txt / .tsv file with circRNA BSJ ratios.

Drag & drop file here or click to browse
📋 sample file format

The file should be tab-delimited, with the first row as column headers, and each subsequent row as a record of a circRNA and its BSJ ratio value.

circRNA_ID	SRR25387918
chr2:32377588|32510634	0.0204081632
chr8:42361096|42362698	0.0587459321
chr3:155893518|155937881	0.321546789
chr2:241407537|241434321	0.1457852
chr1:154258977|154260029	0.501478523

Visualization

Sample Numbers

circRNA Type

Citation

Zheng, X.#, Zhang, J.#, Song, L.#, Li, XJ., Zhao, F.*, & Gao, Y*. (2025) CIRI3: scalable and accurate detection and quantification of circular RNAs in extremely large RNA-seq datasets. Nature Biotechnology.