gpDB,gpDB,gpDB,gpDB,gpDB,gpDB,gpDB,gpDB,gpDB,gpDB,gpDB:,database,GPCRs,,G-proteins,,effectors,interactions,gpDB,publicly,accessible,,relational,database,,containing,information,G-proteins,,G-protein,coupled,receptors,,GPCRs,,effectors,,well,information,concerning,known,interactions,molecules,sequences,classified,according,hierarchy,different,classes,,families,subfamilies,based,literature,search,main,innovation,besides,classification,G-proteins,,GPCRs,effectors,relational,model,database,,describing,known,coupling,specificity,GPCRs,respective,alpha,subunits,G-proteins,,also,specific,interaction,G-proteins,effectors,,unique,feature,available,database.<br>AVAILABILITY:,http://bioinformatics.biol.uoa.gr/gpDB,CONTACT:,shamodr@biol.uoa.gr<br>SUPPLEMENTARY,INFORMATION:,Supplementary,data,available,Bioinformatics,online.<br>A,database,G,proteins,interaction,GPCRs,BACKGROUND:,G,protein-coupled,receptors,,GPCRs,,transduce,signals,extracellular,space,cell,,interaction,G,proteins,,act,switches,forming,hetero-trimers,composed,different,subunits,,alpha,beta,gamma,,alpha,subunit,G,protein,responsible,recognition,given,GPCR,Whereas,specialised,resources,GPCRs,,groups,receptors,,already,available,,currently,,publicly,available,database,focusing,G,Proteins,containing,information,coupling,specificity,respective,receptors.<br>DESCRIPTION:,gpDB,publicly,accessible,G,proteins/GPCRs,relational,database,Including,species,homologs,,database,contains,detailed,information,418,G,protein,monomers,,272,Galpha,,87,Gbeta,59,Ggamma,,2782,GPCRs,sequences,belonging,families,known,coupling,G,proteins,GPCRs,G,proteins,classified,according,hierarchy,different,classes,,families,sub-families,,based,extensive,literature,searchs,main,innovation,besides,classification,G,proteins,GPCRs,relational,model,database,,describing,known,coupling,specificity,GPCRs,respective,alpha,subunit,G,proteins,,unique,feature,available,database,full,sequence,information,cross-references,publicly,available,databases,,references,literature,concerning,coupling,specificity,dimerization,GPCRs,user,may,submit,advanced,queries,text,search,Furthermore,,provide,pattern,search,tool,,interface,running,BLAST,database,interconnectivity,PRED-TMR,,PRED-GPCR,TMRPres2D.<br>CONCLUSIONS:,database,will,useful,,experimentalists,bioinformaticians,,study,G,protein/GPCR,interactions,future,development,predictive,algorithms,available,academics,,via,web,browser,URL:,http://bioinformatics.biol.uoa.gr/gpDB.<br>,gpDB:,database,GPCRs,,G-proteins,,effectors,interactions,gpDB,publicly,accessible,,relational,database,,containing,information,G-proteins,,G-protein,coupled,receptors,,GPCRs,,effectors,,well,information,concerning,known,interactions,molecules,sequences,classified,according,hierarchy,different,classes,,families,subfamilies,based,literature,search,main,innovation,besides,classification,G-proteins,,GPCRs,effectors,relational,model,database,,describing,known,coupling,specificity,GPCRs,respective,alpha,subunits,G-proteins,,also,specific,interaction,G-proteins,effectors,,unique,feature,available,database.<br>AVAILABILITY:,http://bioinformatics.biol.uoa.gr/gpDB,CONTACT:,shamodr@biol.uoa.gr<br>SUPPLEMENTARY,INFORMATION:,Supplementary,data,available,Bioinformatics,online.<br>A,database,G,proteins,interaction,GPCRs,BACKGROUND:,G,protein-coupled,receptors,,GPCRs,,transduce,signals,extracellular,space,cell,,interaction,G,proteins,,act,switches,forming,hetero-trimers,composed,different,subunits,,alpha,beta,gamma,,alpha,subunit,G,protein,responsible,recognition,given,GPCR,Whereas,specialised,resources,GPCRs,,groups,receptors,,already,available,,currently,,publicly,available,database,focusing,G,Proteins,containing,information,coupling,specificity,respective,receptors.<br>DESCRIPTION:,gpDB,publicly,accessible,G,proteins/GPCRs,relational,database,Including,species,homologs,,database,contains,detailed,information,418,G,protein,monomers,,272,Galpha,,87,Gbeta,59,Ggamma,,2782,GPCRs,sequences,belonging,families,known,coupling,G,proteins,GPCRs,G,proteins,classified,according,hierarchy,different,classes,,families,sub-families,,based,extensive,literature,searchs,main,innovation,besides,classification,G,proteins,GPCRs,relational,model,database,,describing,known,coupling,specificity,GPCRs,respective,alpha,subunit,G,proteins,,unique,feature,available,database,full,sequence,information,cross-references,publicly,available,databases,,references,literature,concerning,coupling,specificity,dimerization,GPCRs,user,may,submit,advanced,queries,text,search,Furthermore,,provide,pattern,search,tool,,interface,running,BLAST,database,interconnectivity,PRED-TMR,,PRED-GPCR,TMRPres2D.<br>CONCLUSIONS:,database,will,useful,,experimentalists,bioinformaticians,,study,G,protein/GPCR,interactions,future,development,predictive,algorithms,available,academics,,via,web,browser,URL:,http://bioinformatics.biol.uoa.gr/gpDB.<br>