RCoV19,RCoV19,RCoV19,RCoV19,RCoV19,RCoV19,RCoV19,RCoV19,RCoV19,RCoV19,2019,novel,coronavirus,resource,ongoing,outbreak,novel,coronavirus,infection,Wuhan,,China,since,December,2019,led,31,516,infected,persons,638,deaths,across,25,countries,,till,16:00,February,7,,2020,,virus,causing,pneumonia,named,2019,novel,coronavirus,,2019-nCoV,,World,Health,Organization,promote,data,sharing,make,relevant,information,2019-nCoV,publicly,available,,construct,2019,Novel,Coronavirus,Resource,,2019nCoVR,,https://bigd.big.ac.cn/ncov,,2019nCoVR,features,comprehensive,integration,genomic,proteomic,sequences,well,metadata,information,Global,Initiative,Sharing,Influenza,Data,,National,Center,Biotechnology,Information,,China,National,GeneBank,,National,Microbiology,Data,Center,China,National,Center,Bioinformation,,CNCB,/National,Genomics,Data,Center,,NGDC,,also,incorporates,wide,range,relevant,information,including,scientific,literatures,,news,,popular,articles,science,dissemination,,provides,visualization,functionalities,genome,variation,analysis,results,based,collected,2019-nCoV,strains,Moreover,,linking,seamlessly,related,databases,CNCB/NGDC,,2019nCoVR,offers,virus,data,submission,sharing,services,raw,sequence,reads,assembled,sequences,report,,provide,comprehensive,descriptions,data,deposition,,management,,release,utility,2019nCoVR,,laying,important,foundations,aid,studies,virus,classification,origin,,genome,variation,evolution,,fast,detection,,drug,development,pneumonia,precision,prevention,therapy.A,coronavirus,online,analysis,platform,National,Genomics,Data,Center,Since,COVID-19,outbreak,December,2019,,epidemic,SARS-CoV-2,infection,become,global,pandemic,spread,200,countries,regions,around,world,progress,worldwide,studies,virus,detections,SARS-CoV-2,,large,number,coronavirus,genomes,sequencing,data,accumulated,unprecedented,speed,meet,needs,fast,analyses,SARS-CoV-2,genome,sequences,,National,Genomics,Data,Center,,NGDC,,China,National,Center,Bioinformation,,CNCB,,established,coronavirus,online,analysis,platform,,includes,assembly,,BLAST,,genome,annotation,,variant,identification,,variant,annotation,modules,online,analysis,platform,can,freely,accessed,2019,Novel,Coronavirus,Resource,,2019nCoVR,,,https://bigd.big.ac.cn/ncov/online/tools,.<br>The,Global,Landscape,SARS-CoV-2,Genomes,,Variants,,Haplotypes,2019nCoVR,January,22,,2020,,China,National,Center,Bioinformation,,CNCB,,released,2019,Novel,Coronavirus,Resource,,2019nCoVR,,,open-access,information,resource,severe,acute,respiratory,syndrome,coronavirus,2,,SARS-CoV-2,,2019nCoVR,features,comprehensive,integration,sequence,clinical,information,publicly,available,SARS-CoV-2,isolates,,manually,curated,value-added,annotations,quality,evaluated,automated,in-house,pipeline,particular,note,,2019nCoVR,offers,systematic,analyses,generate,dynamic,landscape,SARS-CoV-2,genomic,variations,global,scale,provides,identified,variants,detailed,statistics,virus,isolate,,congregates,quality,score,,functional,annotation,,population,frequency,variant,Spatiotemporal,change,variant,can,visualized,historical,viral,haplotype,network,maps,course,outbreak,also,generated,based,complete,high-quality,genomes,available,Moreover,,2019nCoVR,provides,full,collection,SARS-CoV-2,relevant,literature,coronavirus,disease,2019,,COVID-19,,,including,published,papers,PubMed,well,preprints,services,bioRxiv,medRxiv,Europe,PMC,Furthermore,,linking,relevant,databases,CNCB,,2019nCoVR,offers,data,submission,services,raw,sequence,reads,assembled,genomes,,data,sharing,NCBI,Collectively,,SARS-CoV-2,updated,daily,collect,latest,information,genome,sequences,,variants,,haplotypes,,literature,timely,reflection,,making,2019nCoVR,valuable,resource,global,research,community,2019nCoVR,accessible,https://bigd.big.ac.cn/ncov/.<br>RCoV19:,One-stop,Hub,SARS-CoV-2,Genome,Data,Integration,,Variant,Monitoring,,Risk,Pre-warning,Resource,Coronavirus,2019,,RCoV19,,open-access,information,resource,dedicated,providing,valuable,data,genomes,,mutations,,variants,severe,acute,respiratory,syndrome,coronavirus,2,,SARS-CoV-2,,updated,implementation,RCoV19,,made,significant,improvements,advancements,previous,version,Firstly,,implemented,highly,refined,genome,data,curation,model,model,now,features,automated,integration,pipeline,optimized,curation,rules,,enabling,efficient,daily,updates,data,RCoV19,Secondly,,developed,global,regional,lineage,evolution,monitoring,platform,,alongside,outbreak,risk,pre-warning,system,additions,provide,comprehensive,understanding,SARS-CoV-2,evolution,transmission,patterns,,enabling,better,preparedness,response,strategies,Thirdly,,developed,powerful,interactive,mutation,spectrum,comparison,module,module,allows,users,compare,analyze,mutation,patterns,,assisting,detection,potential,new,lineages,Furthermore,,incorporated,comprehensive,knowledgebase,mutation,effects,knowledgebase,serves,valuable,resource,retrieving,information,functional,implications,specific,mutations,summary,,RCoV19,serves,vital,scientific,resource,,providing,access,valuable,data,,relevant,information,,technical,support,global,fight,COVID-19,complete,contents,RCoV19,available,public,https://ngdc.cncb.ac.cn/ncov/.<br>,2019,novel,coronavirus,resource,ongoing,outbreak,novel,coronavirus,infection,Wuhan,,China,since,December,2019,led,31,516,infected,persons,638,deaths,across,25,countries,,till,16:00,February,7,,2020,,virus,causing,pneumonia,named,2019,novel,coronavirus,,2019-nCoV,,World,Health,Organization,promote,data,sharing,make,relevant,information,2019-nCoV,publicly,available,,construct,2019,Novel,Coronavirus,Resource,,2019nCoVR,,https://bigd.big.ac.cn/ncov,,2019nCoVR,features,comprehensive,integration,genomic,proteomic,sequences,well,metadata,information,Global,Initiative,Sharing,Influenza,Data,,National,Center,Biotechnology,Information,,China,National,GeneBank,,National,Microbiology,Data,Center,China,National,Center,Bioinformation,,CNCB,/National,Genomics,Data,Center,,NGDC,,also,incorporates,wide,range,relevant,information,including,scientific,literatures,,news,,popular,articles,science,dissemination,,provides,visualization,functionalities,genome,variation,analysis,results,based,collected,2019-nCoV,strains,Moreover,,linking,seamlessly,related,databases,CNCB/NGDC,,2019nCoVR,offers,virus,data,submission,sharing,services,raw,sequence,reads,assembled,sequences,report,,provide,comprehensive,descriptions,data,deposition,,management,,release,utility,2019nCoVR,,laying,important,foundations,aid,studies,virus,classification,origin,,genome,variation,evolution,,fast,detection,,drug,development,pneumonia,precision,prevention,therapy.A,coronavirus,online,analysis,platform,National,Genomics,Data,Center,Since,COVID-19,outbreak,December,2019,,epidemic,SARS-CoV-2,infection,become,global,pandemic,spread,200,countries,regions,around,world,progress,worldwide,studies,virus,detections,SARS-CoV-2,,large,number,coronavirus,genomes,sequencing,data,accumulated,unprecedented,speed,meet,needs,fast,analyses,SARS-CoV-2,genome,sequences,,National,Genomics,Data,Center,,NGDC,,China,National,Center,Bioinformation,,CNCB,,established,coronavirus,online,analysis,platform,,includes,assembly,,BLAST,,genome,annotation,,variant,identification,,variant,annotation,modules,online,analysis,platform,can,freely,accessed,2019,Novel,Coronavirus,Resource,,2019nCoVR,,,https://bigd.big.ac.cn/ncov/online/tools,.<br>The,Global,Landscape,SARS-CoV-2,Genomes,,Variants,,Haplotypes,2019nCoVR,January,22,,2020,,China,National,Center,Bioinformation,,CNCB,,released,2019,Novel,Coronavirus,Resource,,2019nCoVR,,,open-access,information,resource,severe,acute,respiratory,syndrome,coronavirus,2,,SARS-CoV-2,,2019nCoVR,features,comprehensive,integration,sequence,clinical,information,publicly,available,SARS-CoV-2,isolates,,manually,curated,value-added,annotations,quality,evaluated,automated,in-house,pipeline,particular,note,,2019nCoVR,offers,systematic,analyses,generate,dynamic,landscape,SARS-CoV-2,genomic,variations,global,scale,provides,identified,variants,detailed,statistics,virus,isolate,,congregates,quality,score,,functional,annotation,,population,frequency,variant,Spatiotemporal,change,variant,can,visualized,historical,viral,haplotype,network,maps,course,outbreak,also,generated,based,complete,high-quality,genomes,available,Moreover,,2019nCoVR,provides,full,collection,SARS-CoV-2,relevant,literature,coronavirus,disease,2019,,COVID-19,,,including,published,papers,PubMed,well,preprints,services,bioRxiv,medRxiv,Europe,PMC,Furthermore,,linking,relevant,databases,CNCB,,2019nCoVR,offers,data,submission,services,raw,sequence,reads,assembled,genomes,,data,sharing,NCBI,Collectively,,SARS-CoV-2,updated,daily,collect,latest,information,genome,sequences,,variants,,haplotypes,,literature,timely,reflection,,making,2019nCoVR,valuable,resource,global,research,community,2019nCoVR,accessible,https://bigd.big.ac.cn/ncov/.<br>RCoV19:,One-stop,Hub,SARS-CoV-2,Genome,Data,Integration,,Variant,Monitoring,,Risk,Pre-warning,Resource,Coronavirus,2019,,RCoV19,,open-access,information,resource,dedicated,providing,valuable,data,genomes,,mutations,,variants,severe,acute,respiratory,syndrome,coronavirus,2,,SARS-CoV-2,,updated,implementation,RCoV19,,made,significant,improvements,advancements,previous,version,Firstly,,implemented,highly,refined,genome,data,curation,model,model,now,features,automated,integration,pipeline,optimized,curation,rules,,enabling,efficient,daily,updates,data,RCoV19,Secondly,,developed,global,regional,lineage,evolution,monitoring,platform,,alongside,outbreak,risk,pre-warning,system,additions,provide,comprehensive,understanding,SARS-CoV-2,evolution,transmission,patterns,,enabling,better,preparedness,response,strategies,Thirdly,,developed,powerful,interactive,mutation,spectrum,comparison,module,module,allows,users,compare,analyze,mutation,patterns,,assisting,detection,potential,new,lineages,Furthermore,,incorporated,comprehensive,knowledgebase,mutation,effects,knowledgebase,serves,valuable,resource,retrieving,information,functional,implications,specific,mutations,summary,,RCoV19,serves,vital,scientific,resource,,providing,access,valuable,data,,relevant,information,,technical,support,global,fight,COVID-19,complete,contents,RCoV19,available,public,https://ngdc.cncb.ac.cn/ncov/.<br>