The PFAS-Tox Database,The PFAS-Tox Database,The PFAS-Tox Database,The PFAS-Tox Database,The PFAS-Tox Database,The PFAS-Tox Database,The PFAS-Tox Database,The PFAS-Tox Database,The PFAS-Tox Database,The PFAS-Tox Database,PFAS-Tox,Database:,systematic,evidence,map,health,studies,29,per-,polyfluoroalkyl,substances,BACKGROUND:,PFAS,,per-and,polyfluoroalkyl,substances,,large,class,synthetic,chemicals,widely,used,consumer,products,industrial,processes,scientific,literature,PFAS,increased,dramatically,last,decade,Many,stakeholders,,including,regulators,,scientists,,non-governmental,organizations,,concerned,individuals,benefit,efficient,way,access,health,toxicological,literature,related,PFAS.<br>OBJECTIVE:,create,systematic,evidence,map,available,peer-reviewed,health,toxicological,research,29,PFAS.<br>METHODS:,protocol,conducting,systematic,evidence,map,initially,published,Zenodo,,Pelch,et,al,2019c,,,peer,reviewed,published,Environment,International,,Pelch,et,al,2019d,,PubMed,database,searched,January,25,,2021,Studies,screened,inclusion,exclusion,according,Populations,,Exposures,,Comparators,,Outcomes,,PECO,,statement,Inclusion,criteria,intentionally,broad,included,human,,animal,,and/or,vitro,study,investigated,exposure,one,29,PFAS,interest,human,health,toxicological,effect,Selected,study,details,extracted,included,studies,described,protocol,Study,appraisal,conducted,included,studies,extracted,meta-data,freely,available,online,,interactive,systematic,evidence,map,https://pfastoxdatabase.org.<br>RESULTS:,15,000,studies,retrieved,PubMed,literature,searches,manual,screening,,1,067,studies,identified,included,investigating,health,toxicological,effect,one,PFAS,interest,505,human,,385,animal,,220,vitro,studies,Summary,tables,extracted,data,overall,observations,included,report.<br>CONCLUSIONS:,PFAS-Tox,Database,useful,tool,searching,,filtering,,identifying,peer,reviewed,research,health,toxicological,effects,included,PFAS,summary,evidence,map,provide,examples,data,gaps,clusters,revealed,database,,goal,helping,direct,future,research,efforts,,facilitate,systematic,reviews,,e.g,immune,effects,,mixtures,PFAS,,effects,short,chain,PFAS,,,inform,regulatory,risk,assessments,,improve,opportunities,cross-disciplinary,coordination,also,discuss,tool,supports,scientists,,regulatory,agencies,,individuals,increasing,awareness,access,current,evidence,regarding,health,effects,associated,PFAS,exposure.<br>,PFAS-Tox,Database:,systematic,evidence,map,health,studies,29,per-,polyfluoroalkyl,substances,BACKGROUND:,PFAS,,per-and,polyfluoroalkyl,substances,,large,class,synthetic,chemicals,widely,used,consumer,products,industrial,processes,scientific,literature,PFAS,increased,dramatically,last,decade,Many,stakeholders,,including,regulators,,scientists,,non-governmental,organizations,,concerned,individuals,benefit,efficient,way,access,health,toxicological,literature,related,PFAS.<br>OBJECTIVE:,create,systematic,evidence,map,available,peer-reviewed,health,toxicological,research,29,PFAS.<br>METHODS:,protocol,conducting,systematic,evidence,map,initially,published,Zenodo,,Pelch,et,al,2019c,,,peer,reviewed,published,Environment,International,,Pelch,et,al,2019d,,PubMed,database,searched,January,25,,2021,Studies,screened,inclusion,exclusion,according,Populations,,Exposures,,Comparators,,Outcomes,,PECO,,statement,Inclusion,criteria,intentionally,broad,included,human,,animal,,and/or,vitro,study,investigated,exposure,one,29,PFAS,interest,human,health,toxicological,effect,Selected,study,details,extracted,included,studies,described,protocol,Study,appraisal,conducted,included,studies,extracted,meta-data,freely,available,online,,interactive,systematic,evidence,map,https://pfastoxdatabase.org.<br>RESULTS:,15,000,studies,retrieved,PubMed,literature,searches,manual,screening,,1,067,studies,identified,included,investigating,health,toxicological,effect,one,PFAS,interest,505,human,,385,animal,,220,vitro,studies,Summary,tables,extracted,data,overall,observations,included,report.<br>CONCLUSIONS:,PFAS-Tox,Database,useful,tool,searching,,filtering,,identifying,peer,reviewed,research,health,toxicological,effects,included,PFAS,summary,evidence,map,provide,examples,data,gaps,clusters,revealed,database,,goal,helping,direct,future,research,efforts,,facilitate,systematic,reviews,,e.g,immune,effects,,mixtures,PFAS,,effects,short,chain,PFAS,,,inform,regulatory,risk,assessments,,improve,opportunities,cross-disciplinary,coordination,also,discuss,tool,supports,scientists,,regulatory,agencies,,individuals,increasing,awareness,access,current,evidence,regarding,health,effects,associated,PFAS,exposure.<br>