Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database Profile

General information

URL: https://www.RJunBase.org
Full name:
Description: A database of RNA splice junctions in human normal and cancerous tissues
Year founded: 2021
Last update:
Version:
Accessibility:
Manual:
Accessible
Real time : Checking...
Country/Region: China
Data type:
RNA
Data object:
Database category:
Major organism:
Keywords:

Contact information

University/Institution: Fudan University
Address: Institutes of Biomedical Sciences, Fudan University, Shanghai, China,
City:
Province/State:
Country/Region: China
Contact name (PI/Team): Shenglin Huang
Contact email (PI/Helpdesk): slhuang@fudan.edu.cn

Publications

33179749
RJunBase: a database of RNA splice junctions in human normal and cancerous tissues. [PMID: 33179749]
Li Q, Lai H, Li Y, Chen B, Chen S, Li Y, Huang Z, Meng Z, Wang P, Hu Z, Huang S.

Splicing is an essential step of RNA processing for multi-exon genes, in which introns are removed from a precursor RNA, thereby producing mature RNAs containing splice junctions. Here, we develope the RJunBase (www.RJunBase.org), a web-accessible database of three types of RNA splice junctions (linear, back-splice, and fusion junctions) that are derived from RNA-seq data of non-cancerous and cancerous tissues. The RJunBase aims to integrate and characterize all RNA splice junctions of both healthy or pathological human cells and tissues. This new database facilitates the visualization of the gene-level splicing pattern and the junction-level expression profile, as well as the demonstration of unannotated and tumor-specific junctions. The first release of RJunBase contains 682 017 linear junctions, 225 949 back-splice junctions and 34 733 fusion junctions across 18 084 non-cancerous and 11 540 cancerous samples. RJunBase can aid researchers in discovering new splicing-associated targets and provide insights into the identification and assessment of potential neoepitopes for cancer treatment.

Nucleic Acids Res. 2021:49(D1) | 0 Citations (from Europe PMC, 2022-01-15)

Ranking

0
Citations
0
z-index

Community reviews

Not Rated
Data quality & quantity:
Content organization & presentation
System accessibility & reliability:

Word cloud

Related Databases

Record metadata

Created on: 2021-11-15
Curated by:
lin liu [2021-11-15]