Dog 10K genomes project
Dog 10K genomes project (dog10K) was sponsored by Yaping Zhang in KIZ, Robert Wayne in UCLA, and Elaine Ostrander in NIH in November 2015. The aim of the Dog10k is to coordinate the global effort on genome sequencing in dogs and build a comprehensive resource for the canine community. Some of our specific questions are oriented toward understanding the evolutionary history of dogs, genetic changes associated with domestication, and relationships of genetic changes to phenotype. We also have a goal to investigate loci involved in canine susceptibility to disease, particularly among certain breeds.
5-Years Plan
1
stageⅠ:1000
Decipher the demographic history,and genomic effect of artificial selection early in domestication.
2
stageⅡ:5000
Identify the genetic basis of inherited disease,and various phenotypes and behaviors.
3
stageⅢ:10K
Construct a fine scale genomic map for breeds all over the world. Individual breed history,genes under selection in modern breeds and accumulation of deleterious variation.
