ENSG00000000005 - Gene Expression Nebulas

Basic Information Transcripts Gene Ontology Disease Ontology

Accession ID: ENSG00000000005

Source: Ensembl

Gene Symbol: TNMD

Related IDs:

Entrez ID: 64102

HGNC ID: HGNC:17757

Refseq ID: NM_022144; NP_071427;

Location: X:100584936-100599885(+)

Description: tenomodulin

Gene Biotype: protein_coding

Band: q22.1

GC Content: 40.78

HK/TS: NA

Phenotype: NA

GeneCard:

Accession	Transcript Symbol	Chr	Start	End	Strand	Transcript Biotype

GO Term ID	GO Term Name	GO Domain	GO Term Definition
GO:0005634	nucleus	cellular_component	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0005737	cytoplasm	cellular_component	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0016020	membrane	cellular_component	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0016021	integral component of membrane	cellular_component	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0005515	protein binding	molecular_function	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0016525	negative regulation of angiogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
GO:0005635	nuclear envelope	cellular_component	The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
GO:0001886	endothelial cell morphogenesis	biological_process	The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
GO:0001937	negative regulation of endothelial cell proliferation	biological_process	Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
GO:0035990	tendon cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.
GO:0071773	cellular response to BMP stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.

DOID	Parent DOID	Disease Name	Synonyms	Disease Definition
DOID:10603	DOID:4195	glucose intolerance	Malabsorption of glucose;Glucose: malabsorption;Glucose: intolerance
DOID:10871	DOID:2007	age related macular degeneration	Age Related Maculopathies;Age Related Maculopathy;Senile macular degeneration;age-related macular degeneration;Senile macular retinal degeneration	A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.
DOID:4448	DOID:8466	macular degeneration	Macular degeneration of retina	A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.
DOID:9351	DOID:4194	diabetes mellitus		A glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
DOID:1398	DOID:0050117	parasitic infectious disease	Ectoparasitic disease;parasitemia	A disease by infectious agent that is carried out by a parasite which by definition is a pathogen that simultaneously injures and derives sustenance from its host.
DOID:9352	DOID:9351	type 2 diabetes mellitus	type 2 diabetes;non-insulin-dependent diabetes mellitus;NIDDM;type II diabetes mellitus	A diabetes mellitus that involves high blood glucose resulting from cells fail to use insulin properly.
DOID:9970	DOID:654	obesity		An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.

Gene Expression Nebulas

Homo sapiens: ENSG00000000005

Expression Level in GEN

Expression Level in GTEx

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