| GO:0016020 |
membrane |
cellular_component |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| GO:0016021 |
integral component of membrane |
cellular_component |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| GO:0005615 |
extracellular space |
cellular_component |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
| GO:0005886 |
plasma membrane |
cellular_component |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| GO:0005576 |
extracellular region |
cellular_component |
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
| GO:0070062 |
extracellular exosome |
cellular_component |
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
| GO:0001895 |
retina homeostasis |
biological_process |
A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function. |
| GO:0043312 |
neutrophil degranulation |
biological_process |
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil. |
| GO:0005887 |
integral component of plasma membrane |
cellular_component |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
biological_process |
A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. |
| GO:0035577 |
azurophil granule membrane |
cellular_component |
The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. |
| GO:0043113 |
receptor clustering |
biological_process |
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. |
| GO:0043235 |
receptor complex |
cellular_component |
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
| GO:0001580 |
detection of chemical stimulus involved in sensory perception of bitter taste |
biological_process |
The series of events required for a bitter taste stimulus to be received and converted to a molecular signal. |
| GO:0001792 |
polymeric immunoglobulin receptor activity |
molecular_function |
Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
| GO:0002415 |
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin recep |
biological_process |
The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa. |
| GO:0038093 |
Fc receptor signaling pathway |
biological_process |
A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. |
