| GO:0005524 |
ATP binding |
molecular_function |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| GO:0006468 |
protein phosphorylation |
biological_process |
The process of introducing a phosphate group on to a protein. |
| GO:0004674 |
protein serine/threonine kinase activity |
molecular_function |
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
| GO:0004672 |
protein kinase activity |
molecular_function |
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. |
| GO:0005634 |
nucleus |
cellular_component |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| GO:0005737 |
cytoplasm |
cellular_component |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| GO:0000166 |
nucleotide binding |
molecular_function |
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
| GO:0016301 |
kinase activity |
molecular_function |
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. |
| GO:0016740 |
transferase activity |
molecular_function |
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
| GO:0016310 |
phosphorylation |
biological_process |
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
| GO:0008033 |
tRNA processing |
biological_process |
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. |
| GO:0016787 |
hydrolase activity |
molecular_function |
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. |
| GO:0005515 |
protein binding |
molecular_function |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
| GO:0005654 |
nucleoplasm |
cellular_component |
That part of the nuclear content other than the chromosomes or the nucleolus. |
| GO:1901796 |
regulation of signal transduction by p53 class mediator |
biological_process |
Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator. |
| GO:0070525 |
tRNA threonylcarbamoyladenosine metabolic process |
biological_process |
The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. |
| GO:0000408 |
EKC/KEOPS complex |
cellular_component |
A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p. |
| GO:0002039 |
p53 binding |
molecular_function |
Interacting selectively and non-covalently with one of the p53 family of proteins. |
