ENSG00000204138 - Gene Expression Nebulas

A data portal of transcriptomic profiles analyzed by a unified pipeline across multiple species

GO Term ID	GO Term Name	GO Domain	GO Term Definition
GO:0019888	protein phosphatase regulator activity	molecular_function	Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
GO:0003779	actin binding	molecular_function	Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
GO:0008157	protein phosphatase 1 binding	molecular_function	Interacting selectively and non-covalently with the enzyme protein phosphatase 1.
GO:0005737	cytoplasm	cellular_component	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0042995	cell projection	cellular_component	A prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0007275	multicellular organism development	biological_process	The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0043666	regulation of phosphoprotein phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein.
GO:0007399	nervous system development	biological_process	The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
GO:0030027	lamellipodium	cellular_component	A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
GO:0051726	regulation of cell cycle	biological_process	Any process that modulates the rate or extent of progression through the cell cycle.
GO:0030036	actin cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
GO:0007266	Rho protein signal transduction	biological_process	A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
GO:0001843	neural tube closure	biological_process	The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
GO:0001755	neural crest cell migration	biological_process	The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
GO:0072542	protein phosphatase activator activity	molecular_function	Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
GO:0043085	positive regulation of catalytic activity	biological_process	Any process that activates or increases the activity of an enzyme.
GO:0061386	closure of optic fissure	biological_process	The closure of the temporary ventral gap in the optic cup that contributes to its shaping.
GO:0048484	enteric nervous system development	biological_process	The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.
GO:2001045	negative regulation of integrin-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway.
GO:0032515	negative regulation of phosphoprotein phosphatase activity	biological_process	Any process that stops or reduces the activity of a phosphoprotein phosphatase.
GO:0004864	protein phosphatase inhibitor activity	molecular_function	Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.

GO Term ID

GO Term Name

GO Domain

GO Term Definition

GO:0019888

protein phosphatase regulator activity

molecular_function

Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.

GO:0003779

actin binding

molecular_function

Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.

GO:0008157

protein phosphatase 1 binding

molecular_function

Interacting selectively and non-covalently with the enzyme protein phosphatase 1.

GO:0005737

cytoplasm

cellular_component

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0042995

cell projection

cellular_component

A prolongation or process extending from a cell, e.g. a flagellum or axon.

GO:0007275

multicellular organism development

biological_process

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

GO:0043666

regulation of phosphoprotein phosphatase activity

biological_process

Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein.

GO:0007399

nervous system development

biological_process

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

GO:0030027

lamellipodium

cellular_component

A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.

GO:0051726

regulation of cell cycle

biological_process

Any process that modulates the rate or extent of progression through the cell cycle.

GO:0030036

actin cytoskeleton organization

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.

GO:0007266

Rho protein signal transduction

biological_process

A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.

GO:0001843

neural tube closure

biological_process

The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.

GO:0001755

neural crest cell migration

biological_process

The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.

GO:0072542

protein phosphatase activator activity

molecular_function

Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.

GO:0043085

positive regulation of catalytic activity

biological_process

Any process that activates or increases the activity of an enzyme.

GO:0061386

closure of optic fissure

biological_process

The closure of the temporary ventral gap in the optic cup that contributes to its shaping.

GO:0048484

enteric nervous system development

biological_process

The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.

GO:2001045

negative regulation of integrin-mediated signaling pathway

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway.

GO:0032515

negative regulation of phosphoprotein phosphatase activity

biological_process

Any process that stops or reduces the activity of a phosphoprotein phosphatase.

GO:0004864

protein phosphatase inhibitor activity

molecular_function

Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.

Average TPM	Median TPM	Maximum TPM	Minimum TPM	CV	τ-Value	Tissue Breadth	GTEx	REDIportal
14.14	14.49	34.30	3.24	0.52	0.60	53

Average TPM

Median TPM

Maximum TPM

Minimum TPM

τ-Value

Tissue Breadth

GTEx

REDIportal

14.14

14.49

34.30

3.24

0.52

0.60

Gene Expression Nebulas

Homo sapiens: ENSG00000204138

Expression Level in GEN

Expression Level in GTEx

Coverage level, editing level, editing site visualization with JBrowse