Data Resource | Project ID | BioProject ID | Title | Strategy | Species | Tissue | Cell Type | Cell Line | Disease | Sample Number | Summary | Overall Design | PMID | Release Date | Submission Date | Update Date |
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Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors.
Segal JM, Kent D, Wesche DJ, Ng SS, Serra M, Oulès B, Kar G, Emerton G, Blackford SJI, Darmanis S, Miquel R, Luong TV, Yamamoto R, Bonham A, Jassem W, Heaton N, Vigilante A, King A, Sancho R, Teichmann S, Quake SR, Nakauchi H, Rashid ST.
Nat Commun. 2019-07-26; 10 (1)
PMID: 31350390 DOI: 10.1038/s41467-019-11266-x
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Interferon-regulated genetic programs and JAK/STAT pathway activate the intronic promoter of the short ACE2 isoform in renal proximal tubules.
Jankowski J, Lee HK, Wilflingseder J, Hennighausen L.
bioRxiv. 2021-01-19;
PMID: 33501441 DOI: 10.1101/2021.01.15.426908
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Airway Smooth Muscle-Specific Transcriptomic Signatures of Glucocorticoid Exposure.
Kan M, Koziol-White C, Shumyatcher M, Johnson M, Jester W, Panettieri RA, Himes BE.
Am J Respir Cell Mol Biol. 2019-07-01; 61 (1)
PMID: 30694689 DOI: 10.1165/rcmb.2018-0385oc
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RNA-seq Analysis Reveals Unique Transcriptome Signatures in Systemic Lupus Erythematosus Patients with Distinct Autoantibody Specificities.
Rai R, Chauhan SK, Singh VV, Rai M, Rai G.
PLoS One. 2016-11-11; 11 (11)
PMID: 27835693 DOI: 10.1371/journal.pone.0166312
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Rhinovirus Infections in Individuals with Asthma Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19.
Chang EH, Willis AL, Romanoski CE, Cusanovich DA, Pouladi N, Li J, Lussier YA, Martinez FD.
Am J Respir Crit Care Med. 2020-09-01; 202 (5)
PMID: 32649217 DOI: 10.1164/rccm.202004-1343le
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Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community.
Lee HK, Knabl L, Pipperger L, Volland A, Furth PA, Kang K, Smith HE, Knabl L, Bellmann R, Bernhard C, Kaiser N, Gänzer H, Ströhle M, Walser A, von Laer D, Hennighausen L.
Sci Rep. 2021-02-19; 11 (1)
PMID: 33608566 DOI: 10.1038/s41598-021-83110-6
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Disease-specific regulation of gene expression in a comparative analysis of juvenile idiopathic arthritis and inflammatory bowel disease.
Mo A, Marigorta UM, Arafat D, Chan LHK, Ponder L, Jang SR, Prince J, Kugathasan S, Prahalad S, Gibson G.
Genome Med. 2018-06-27; 10 (1)
PMID: 29950172 DOI: 10.1186/s13073-018-0558-x
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Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing.
Smith SL, Kennedy PR, Stacey KB, Worboys JD, Yarwood A, Seo S, Solloa EH, Mistretta B, Chatterjee SS, Gunaratne P, Allette K, Wang YC, Smith ML, Sebra R, Mace EM, Horowitz A, Thomson W, Martin P, Eyre S, Davis DM.
Blood Adv. 2020-04-01; 4 (7)
PMID: 32271902 DOI: 10.1182/bloodadvances.2019000699
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Fixed single-cell transcriptomic characterization of human radial glial diversity.
Thomsen ER, Mich JK, Yao Z, Hodge RD, Doyle AM, Jang S, Shehata SI, Nelson AM, Shapovalova NV, Levi BP, Ramanathan S.
Nat Methods. 2015-11-16; 13 (1)
PMID: 26524239 DOI: 10.1038/nmeth.3629
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Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation.
Matute J, Finander B, Pepin D, Ai X, Smith N, Li J, Edlow A, Villani A, Lerou P, Kalish B.
Res Sq. 2021-03-16;
PMID: 33758834 DOI: 10.21203/rs.3.rs-311000/v1
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Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19.
Liu C, Martins AJ, Lau WW, Rachmaninoff N, Chen J, Imberti L, Mostaghimi D, Fink DL, Burbelo PD, Dobbs K, Delmonte OM, Bansal N, Failla L, Sottini A, Quiros-Roldan E, Han KL, Sellers BA, Cheung F, Sparks R, Chun TW, Moir S, Lionakis MS, NIAID COVID Consortium, COVID Clinicians, Rossi C, Su HC, Kuhns DB, Cohen JI, Notarangelo LD, Tsang JS.
Cell. 2021-02-10; 184 (7)
PMID: 33713619 DOI: 10.1016/j.cell.2021.02.018
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Resident T Cells in Resolved Psoriasis Steer Tissue Responses that Stratify Clinical Outcome.
Gallais Sérézal I, Classon C, Cheuk S, Barrientos-Somarribas M, Wadman E, Martini E, Chang D, Xu Landén N, Ehrström M, Nylén S, Eidsmo L.
J Invest Dermatol. 2018-03-03; 138 (8)
PMID: 29510191 DOI: 10.1016/j.jid.2018.02.030
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Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration.
Menon M, Mohammadi S, Davila-Velderrain J, Goods BA, Cadwell TD, Xing Y, Stemmer-Rachamimov A, Shalek AK, Love JC, Kellis M, Hafler BP.
Nat Commun. 2019-10-25; 10 (1)
PMID: 31653841 DOI: 10.1038/s41467-019-12780-8
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A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation.
Grubman A, Chew G, Ouyang JF, Sun G, Choo XY, McLean C, Simmons RK, Buckberry S, Vargas-Landin DB, Poppe D, Pflueger J, Lister R, Rackham OJL, Petretto E, Polo JM.
Nat Neurosci. 2019-12-01; 22 (12)
PMID: 31768052 DOI: 10.1038/s41593-019-0539-4
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Genomic analysis of DNA repair genes and androgen signaling in prostate cancer.
Jividen K, Kedzierska KZ, Yang CS, Szlachta K, Ratan A, Paschal BM.
BMC Cancer. 2018-10-10; 18 (1)
PMID: 30305041 DOI: 10.1186/s12885-018-4848-x
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Nasal ciliated cells are primary targets for SARS-CoV-2 replication in the early stage of COVID-19.
Ahn JH, Kim J, Hong SP, Choi SY, Yang MJ, Ju YS, Kim YT, Kim HM, Rahman MDT, Chung MK, Hong SD, Bae H, Lee CS, Koh GY.
J Clin Invest. 2021-07-01; 131 (13)
PMID: 34003804 DOI: 10.1172/jci148517
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Two distinct immunopathological profiles in autopsy lungs of COVID-19.
Nienhold R, Ciani Y, Koelzer VH, Tzankov A, Haslbauer JD, Menter T, Schwab N, Henkel M, Frank A, Zsikla V, Willi N, Kempf W, Hoyler T, Barbareschi M, Moch H, Tolnay M, Cathomas G, Demichelis F, Junt T, Mertz KD.
Nat Commun. 2020-10-08; 11 (1)
PMID: 33033248 DOI: 10.1038/s41467-020-18854-2
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RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients.
Venken K, Jacques P, Mortier C, Labadia ME, Decruy T, Coudenys J, Hoyt K, Wayne AL, Hughes R, Turner M, Van Gassen S, Martens L, Smith D, Harcken C, Wahle J, Wang CT, Verheugen E, Schryvers N, Varkas G, Cypers H, Wittoek R, Piette Y, Gyselbrecht L, Van Calenbergh S, Van den Bosch F, Saeys Y, Nabozny G, Elewaut D.
Nat Commun. 2019-01-02; 10 (1)
PMID: 30602780 DOI: 10.1038/s41467-018-07911-6
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Triple DMARD treatment in early rheumatoid arthritis modulates synovial T cell activation and plasmablast/plasma cell differentiation pathways.
Walsh AM, Wechalekar MD, Guo Y, Yin X, Weedon H, Proudman SM, Smith MD, Nagpal S.
PLoS One. 2017-09-01; 12 (9)
PMID: 28863153 DOI: 10.1371/journal.pone.0183928
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Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human.
Zhao J, Zhang S, Liu Y, He X, Qu M, Xu G, Wang H, Huang M, Pan J, Liu Z, Li Z, Liu L, Zhang Z.
Cell Discov. 2020-04-28; 6
PMID: 32351704 DOI: 10.1038/s41421-020-0157-z
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Memory CD4+ T cells are generated in the human fetal intestine.
Li N, van Unen V, Abdelaal T, Guo N, Kasatskaya SA, Ladell K, McLaren JE, Egorov ES, Izraelson M, Chuva de Sousa Lopes SM, Höllt T, Britanova OV, Eggermont J, de Miranda NFCC, Chudakov DM, Price DA, Lelieveldt BPF, Koning F.
Nat Immunol. 2019-01-21; 20 (3)
PMID: 30664737 DOI: 10.1038/s41590-018-0294-9
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Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium.
McCauley KB, Alysandratos KD, Jacob A, Hawkins F, Caballero IS, Vedaie M, Yang W, Slovik KJ, Morley M, Carraro G, Kook S, Guttentag SH, Stripp BR, Morrisey EE, Kotton DN.
Stem Cell Reports. 2018-04-12; 10 (5)
PMID: 29657097 DOI: 10.1016/j.stemcr.2018.03.013
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Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface.
Pavličev M, Wagner GP, Chavan AR, Owens K, Maziarz J, Dunn-Fletcher C, Kallapur SG, Muglia L, Jones H.
Genome Res. 2017-02-07; 27 (3)
PMID: 28174237 DOI: 10.1101/gr.207597.116
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Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output.
Giandomenico SL, Mierau SB, Gibbons GM, Wenger LMD, Masullo L, Sit T, Sutcliffe M, Boulanger J, Tripodi M, Derivery E, Paulsen O, Lakatos A, Lancaster MA.
Nat Neurosci. 2019-03-18; 22 (4)
PMID: 30886407 DOI: 10.1038/s41593-019-0350-2
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Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses.
Mick E, Kamm J, Pisco AO, Ratnasiri K, Babik JM, Castañeda G, DeRisi JL, Detweiler AM, Hao SL, Kangelaris KN, Kumar GR, Li LM, Mann SA, Neff N, Prasad PA, Serpa PH, Shah SJ, Spottiswoode N, Tan M, Calfee CS, Christenson SA, Kistler A, Langelier C.
Nat Commun. 2020-11-17; 11 (1)
PMID: 33203890 DOI: 10.1038/s41467-020-19587-y
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Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny.
Classe M, Yao H, Mouawad R, Creighton CJ, Burgess A, Allanic F, Wassef M, Leroy X, Verillaud B, Mortuaire G, Bielle F, Le Tourneau C, Kurtz JE, Khayat D, Su X, Malouf GG.
Cell Rep. 2018-10-01; 25 (3)
PMID: 30332658 DOI: 10.1016/j.celrep.2018.09.047
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Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms.
Li B, Tsoi LC, Swindell WR, Gudjonsson JE, Tejasvi T, Johnston A, Ding J, Stuart PE, Xing X, Kochkodan JJ, Voorhees JJ, Kang HM, Nair RP, Abecasis GR, Elder JT.
J Invest Dermatol. 2014-01-17; 134 (7)
PMID: 24441097 DOI: 10.1038/jid.2014.28
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Transcriptomic characteristics and impaired immune function of patients who retest positive for SARS-CoV-2 RNA.
Wang D, Wang D, Huang M, Zheng X, Shen Y, Fu B, Zhao H, Chen X, Peng P, Zhu Q, Zhou Y, Zhang J, Tian Z, Guan W, Wang G, Wei H.
J Mol Cell Biol. 2021-12-01; 13 (10)
PMID: 34687295 DOI: 10.1093/jmcb/mjab067
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Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients.
Youngs J, Provine NM, Lim N, Sharpe HR, Amini A, Chen YL, Luo J, Edmans MD, Zacharopoulou P, Chen W, Sampson O, Paton R, Hurt WJ, Duncan DA, McNaughton AL, Miao VN, Leaver S, Wyncoll DLA, Ball J, Hopkins P, Oxford Immunology Network Covid-19 response T cell Consortium, Oxford Protective T cell Immunology for COVID-19 (OPTIC) Clinical team, Skelly DT, Barnes E, Dunachie S, Ogg G, Lambe T, Pavord I, Shalek AK, Thompson CP, Xue L, Macallan DC, Goulder P, Klenerman P, Bicanic T.
PLoS Pathog. 2021-09-16; 17 (9)
PMID: 34529726 DOI: 10.1371/journal.ppat.1009804
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Longitudinal Transcriptome Analysis Reveals a Sustained Differential Gene Expression Signature in Patients Treated for Acute Lyme Disease.
Bouquet J, Soloski MJ, Swei A, Cheadle C, Federman S, Billaud JN, Rebman AW, Kabre B, Halpert R, Boorgula M, Aucott JN, Chiu CY.
mBio. 2016-02-12; 7 (1)
PMID: 26873097 DOI: 10.1128/mbio.00100-16
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Persistent viral activity, cytokine storm, and lung fibrosis in a case of severe COVID-19.
Xu G, Liu Y, Liao M, Gou J, Wang X, Yuan J, Liu W, Zhou G, Zhang S, Liu L, Zhang Z.
Clin Transl Med. 2020-11-01; 10 (7)
PMID: 33252859 DOI: 10.1002/ctm2.224
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Single-Cell Sequencing of Glioblastoma Reveals Central Nervous System Susceptibility to SARS-CoV-2.
Wu B, Wang W, Wang H, Zou Q, Hu B, Ye L, Hu Y, Xie Y, Huang N, Lan Q, Cheng H, Dong J, Dai X.
Front Oncol. 2020-11-16; 10
PMID: 33312949 DOI: 10.3389/fonc.2020.566599
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Large-Scale Multi-omic Analysis of COVID-19 Severity.
Overmyer KA, Shishkova E, Miller IJ, Balnis J, Bernstein MN, Peters-Clarke TM, Meyer JG, Quan Q, Muehlbauer LK, Trujillo EA, He Y, Chopra A, Chieng HC, Tiwari A, Judson MA, Paulson B, Brademan DR, Zhu Y, Serrano LR, Linke V, Drake LA, Adam AP, Schwartz BS, Singer HA, Swanson S, Mosher DF, Stewart R, Coon JJ, Jaitovich A.
Cell Syst. 2020-10-08; 12 (1)
PMID: 33096026 DOI: 10.1016/j.cels.2020.10.003
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Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19.
Theobald SJ, Simonis A, Georgomanolis T, Kreer C, Zehner M, Eisfeld HS, Albert MC, Chhen J, Motameny S, Erger F, Fischer J, Malin JJ, Gräb J, Winter S, Pouikli A, David F, Böll B, Koehler P, Vanshylla K, Gruell H, Suárez I, Hallek M, Fätkenheuer G, Jung N, Cornely OA, Lehmann C, Tessarz P, Altmüller J, Nürnberg P, Kashkar H, Klein F, Koch M, Rybniker J.
EMBO Mol Med. 2021-06-16; 13 (8)
PMID: 34133077 DOI: 10.15252/emmm.202114150
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Pain-Associated Transcriptome Changes in Synovium of Knee Osteoarthritis Patients.
Bratus-Neuenschwander A, Castro-Giner F, Frank-Bertoncelj M, Aluri S, Fucentese SF, Schlapbach R, Sprott H.
Genes (Basel). 2018-07-04; 9 (7)
PMID: 29973527 DOI: 10.3390/genes9070338
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FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders.
Mariani J, Coppola G, Zhang P, Abyzov A, Provini L, Tomasini L, Amenduni M, Szekely A, Palejev D, Wilson M, Gerstein M, Grigorenko EL, Chawarska K, Pelphrey KA, Howe JR, Vaccarino FM.
Cell. 2015-07-01; 162 (2)
PMID: 26186191 DOI: 10.1016/j.cell.2015.06.034
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Single-cell RNA sequencing reveals metallothionein heterogeneity during hESC differentiation to definitive endoderm.
Lu J, Baccei A, Lummertz da Rocha E, Guillermier C, McManus S, Finney LA, Zhang C, Steinhauser ML, Li H, Lerou PH.
Stem Cell Res. 2018-01-31; 28
PMID: 29427839 DOI: 10.1016/j.scr.2018.01.015
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Regulatory KIR+ RA+ T cells accumulate with age and are highly activated during viral respiratory disease.
Pieren DKJ, Smits NAM, Hoeboer J, Kandiah V, Postel RJ, Mariman R, van Beek J, van Baarle D, de Wit J, Guichelaar T.
Aging Cell. 2021-05-27; 20 (6)
PMID: 34043881 DOI: 10.1111/acel.13372
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A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn's disease patients.
Li Yim AYF, de Bruyn JR, Duijvis NW, Sharp C, Ferrero E, de Jonge WJ, Wildenberg ME, Mannens MMAM, Buskens CJ, D'Haens GR, Henneman P, Te Velde AA.
PLoS One. 2018-12-27; 13 (12)
PMID: 30589872 DOI: 10.1371/journal.pone.0209656
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Transcriptome of nasopharyngeal samples from COVID-19 patients and a comparative analysis with other SARS-CoV-2 infection models reveal disparate host responses against SARS-CoV-2.
Islam ABMMK, Khan MA, Ahmed R, Hossain MS, Kabir SMT, Islam MS, Siddiki AMAMZ.
J Transl Med. 2021-01-07; 19 (1)
PMID: 33413422 DOI: 10.1186/s12967-020-02695-0
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Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis.
Cao Y, Goods BA, Raddassi K, Nepom GT, Kwok WW, Love JC, Hafler DA.
Sci Transl Med. 2015-05-01; 7 (287)
PMID: 25972006 DOI: 10.1126/scitranslmed.aaa8038
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Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response.
Horning AM, Wang Y, Lin CK, Louie AD, Jadhav RR, Hung CN, Wang CM, Lin CL, Kirma NB, Liss MA, Kumar AP, Sun L, Liu Z, Chao WT, Wang Q, Jin VX, Chen CL, Huang TH.
Cancer Res. 2017-12-12; 78 (4)
PMID: 29233929 DOI: 10.1158/0008-5472.can-17-1924
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Genome wide abnormal DNA methylome of human blastocyst in assisted reproductive technology.
Li G, Yu Y, Fan Y, Li C, Xu X, Duan J, Li R, Kang X, Ma X, Chen X, Ke Y, Yan J, Lian Y, Liu P, Zhao Y, Zhao H, Chen Y, Sun X, Liu J, Qiao J, Liu J.
J Genet Genomics. 2017-09-06; 44 (10)
PMID: 29037989 DOI: 10.1016/j.jgg.2017.09.001
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Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity.
Vono M, Huttner A, Lemeille S, Martinez-Murillo P, Meyer B, Baggio S, Sharma S, Thiriard A, Marchant A, Godeke GJ, Reusken C, Alvarez C, Perez-Rodriguez F, Eckerle I, Kaiser L, Loevy N, Eberhardt CS, Blanchard-Rohner G, Siegrist CA, Didierlaurent AM.
Cell Rep. 2021-09-15; 37 (1)
PMID: 34587479 DOI: 10.1016/j.celrep.2021.109773
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Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients.
Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Cerro Chiang G, Kassar AG, Patel N, Green CER, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P.
Cell Rep. 2020-12-16; 34 (1)
PMID: 33357411 DOI: 10.1016/j.celrep.2020.108590
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Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline.
Hennrich ML, Romanov N, Horn P, Jaeger S, Eckstein V, Steeples V, Ye F, Ding X, Poisa-Beiro L, Lai MC, Lang B, Boultwood J, Luft T, Zaugg JB, Pellagatti A, Bork P, Aloy P, Gavin AC, Ho AD.
Nat Commun. 2018-10-01; 9 (1)
PMID: 30275468 DOI: 10.1038/s41467-018-06353-4
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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans.
Arunachalam PS, Wimmers F, Mok CKP, Perera RAPM, Scott M, Hagan T, Sigal N, Feng Y, Bristow L, Tak-Yin Tsang O, Wagh D, Coller J, Pellegrini KL, Kazmin D, Alaaeddine G, Leung WS, Chan JMC, Chik TSH, Choi CYC, Huerta C, Paine McCullough M, Lv H, Anderson E, Edupuganti S, Upadhyay AA, Bosinger SE, Maecker HT, Khatri P, Rouphael N, Peiris M, Pulendran B.
Science. 2020-08-11; 369 (6508)
PMID: 32788292 DOI: 10.1126/science.abc6261
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Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3' Splice Site Selection through Use of a Different Branch Point.
Darman RB, Seiler M, Agrawal AA, Lim KH, Peng S, Aird D, Bailey SL, Bhavsar EB, Chan B, Colla S, Corson L, Feala J, Fekkes P, Ichikawa K, Keaney GF, Lee L, Kumar P, Kunii K, MacKenzie C, Matijevic M, Mizui Y, Myint K, Park ES, Puyang X, Selvaraj A, Thomas MP, Tsai J, Wang JY, Warmuth M, Yang H, Zhu P, Garcia-Manero G, Furman RR, Yu L, Smith PG, Buonamici S.
Cell Rep. 2015-10-22; 13 (5)
PMID: 26565915 DOI: 10.1016/j.celrep.2015.09.053
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Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development.
Hochane M, van den Berg PR, Fan X, Bérenger-Currias N, Adegeest E, Bialecka M, Nieveen M, Menschaart M, Chuva de Sousa Lopes SM, Semrau S.
PLoS Biol. 2019-02-21; 17 (2)
PMID: 30789893 DOI: 10.1371/journal.pbio.3000152
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Clinico-histopathologic and single nuclei RNA sequencing insights into cardiac injury and microthrombi in critical COVID-19.
Brener MI, Hulke ML, Fukuma N, Golob S, Zilinyi RS, Zhou Z, Tzimas C, Russo I, McGroder C, Pfeiffer RD, Chong A, Zhang G, Burkhoff D, Leon MB, Maurer MS, Moses JW, Uhlemann AC, Hibshoosh H, Uriel N, Szabolcs MJ, Redfors B, Marboe CC, Baldwin MR, Tucker NR, Tsai EJ.
JCI Insight. 2021-12-14;
PMID: 34905515 DOI: 10.1172/jci.insight.154633
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Virus-induced senescence is a driver and therapeutic target in COVID-19.
Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, Richter-Pechanska P, Wyler E, Belenki D, Kaltenbrunner S, Pammer M, Kausche L, Firsching TC, Dietert K, Schotsaert M, Martínez-Romero C, Singh G, Kunz S, Niemeyer D, Ghanem R, Salzer HJF, Paar C, Mülleder M, Uccellini M, Michaelis EG, Khan A, Lau A, Schönlein M, Habringer A, Tomasits J, Adler JM, Kimeswenger S, Gruber AD, Hoetzenecker W, Steinkellner H, Purfürst B, Motz R, Di Pierro F, Lamprecht B, Osterrieder N, Landthaler M, Drosten C, García-Sastre A, Langer R, Ralser M, Eils R, Reimann M, Fan DNY, Schmitt CA.
Nature. 2021-09-13;
PMID: 34517409 DOI: 10.1038/s41586-021-03995-1
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Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis.
Patil VS, Madrigal A, Schmiedel BJ, Clarke J, O'Rourke P, de Silva AD, Harris E, Peters B, Seumois G, Weiskopf D, Sette A, Vijayanand P.
Sci Immunol. 2018-01-01; 3 (19)
PMID: 29352091 DOI: 10.1126/sciimmunol.aan8664
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Electrical and synaptic integration of glioma into neural circuits.
Venkatesh HS, Morishita W, Geraghty AC, Silverbush D, Gillespie SM, Arzt M, Tam LT, Espenel C, Ponnuswami A, Ni L, Woo PJ, Taylor KR, Agarwal A, Regev A, Brang D, Vogel H, Hervey-Jumper S, Bergles DE, Suvà ML, Malenka RC, Monje M.
Nature. 2019-09-18; 573 (7775)
PMID: 31534222 DOI: 10.1038/s41586-019-1563-y
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Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory Response.
Wu H, Malone AF, Donnelly EL, Kirita Y, Uchimura K, Ramakrishnan SM, Gaut JP, Humphreys BD.
J Am Soc Nephrol. 2018-07-06; 29 (8)
PMID: 29980650 DOI: 10.1681/asn.2018020125
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Single-cell multiomics sequencing and analyses of human colorectal cancer.
Bian S, Hou Y, Zhou X, Li X, Yong J, Wang Y, Wang W, Yan J, Hu B, Guo H, Wang J, Gao S, Mao Y, Dong J, Zhu P, Xiu D, Yan L, Wen L, Qiao J, Tang F, Fu W.
Science. 2018-11-01; 362 (6418)
PMID: 30498128 DOI: 10.1126/science.aao3791
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A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.
Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I.
Cell Syst. 2016-09-22; 3 (4)
PMID: 27667365 DOI: 10.1016/j.cels.2016.08.011
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Organoid single cell profiling identifies a transcriptional signature of glomerular disease.
Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, Spence JR, Bitzer M, Troyanskaya OG, Hodgin JB, Wiggins RC, Freedman BS, Kretzler M, European Renal cDNA Bank (ERCB), Nephrotic Syndrome Study Network (NEPTUNE).
JCI Insight. 2019-01-10; 4 (1)
PMID: 30626756 DOI: 10.1172/jci.insight.122697
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Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome.
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Nat Commun. 2019-09-02; 10 (1)
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