Gene Expression Nebulas
A data portal of transcriptomic profiles across multiple species

Gene Expression Nebulas

A data portal of transcriptome profiles across multiple species

Basic Information

Latin Name: Mus musculus
Common Name: House mouse
Kingdom: Animalia
Division: Rodents
Taxonomy ID: 10090
Parent Taxonomy ID: 862507

Datasets

Download Dataset ID BioProject ID Project ID Dataset Name Species Strategy Sample Number Tissue Cell Type Cell Line Healthy Condition Development Stage Case Detail Control Detail Cell Number Biological Condition Quality and Quantity
Baseline Genetic Phenotypic Environmental Spatial Temporal RNA Type Median Mapping Quality Median Coverage Max Sequencing Length Max Replicate#

Publications

Scleral hypoxia is a target for myopia control.
Wu H, Chen W, Zhao F, Zhou Q, Reinach PS, Deng L, Ma L, Luo S, Srinivasalu N, Pan M, Hu Y, Pei X, Sun J, Ren R, Xiong Y, Zhou Z, Zhang S, Tian G, Fang J, Zhang L, Lang J, Wu D, Zeng C, Qu J, Zhou X.
Proc Natl Acad Sci U S A. 2018-07-09; 115 (30)
Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice.
Ryu S, Shchukina I, Youm YH, Qing H, Hilliard B, Dlugos T, Zhang X, Yasumoto Y, Booth CJ, Fernández-Hernando C, Suárez Y, Khanna K, Horvath TL, Dietrich MO, Artyomov M, Wang A, Dixit VD.
Elife. 2021-06-21; 10
IL-13 is a driver of COVID-19 severity.
Donlan AN, Sutherland TE, Marie C, Preissner S, Bradley BT, Carpenter RM, Sturek JM, Ma JZ, Moreau GB, Donowitz JR, Buck GA, Serrano MG, Burgess SL, Abhyankar MM, Mura C, Bourne PE, Preissner R, Young MK, Lyons GR, Loomba JJ, Ratcliffe SJ, Poulter MD, Mathers AJ, Day AJ, Mann BJ, Allen JE, Petri WA.
JCI Insight. 2021-08-09; 6 (15)
Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection.
Winkler ES, Gilchuk P, Yu J, Bailey AL, Chen RE, Chong Z, Zost SJ, Jang H, Huang Y, Allen JD, Case JB, Sutton RE, Carnahan RH, Darling TL, Boon ACM, Mack M, Head RD, Ross TM, Crowe JE, Diamond MS.
Cell. 2021-02-12; 184 (7)
Cell fixation and preservation for droplet-based single-cell transcriptomics.
Alles J, Karaiskos N, Praktiknjo SD, Grosswendt S, Wahle P, Ruffault PL, Ayoub S, Schreyer L, Boltengagen A, Birchmeier C, Zinzen R, Kocks C, Rajewsky N.
BMC Biol. 2017-05-19; 15 (1)
Ultraconserved Enhancers Are Required for Normal Development.
Dickel DE, Ypsilanti AR, Pla R, Zhu Y, Barozzi I, Mannion BJ, Khin YS, Fukuda-Yuzawa Y, Plajzer-Frick I, Pickle CS, Lee EA, Harrington AN, Pham QT, Garvin TH, Kato M, Osterwalder M, Akiyama JA, Afzal V, Rubenstein JLR, Pennacchio LA, Visel A.
Cell. 2018-01-18; 172 (3)
CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma.
Geng J, Chen L, Yuan Y, Wang K, Wang Y, Qin C, Wu G, Chen R, Zhang Z, Wei D, Du P, Zhang J, Lin P, Zhang K, Deng Y, Xu K, Liu J, Sun X, Guo T, Yang X, Wu J, Jiang J, Li L, Zhang K, Wang Z, Zhang J, Yan Q, Zhu H, Zheng Z, Miao J, Fu X, Yang F, Chen X, Tang H, Zhang Y, Shi Y, Zhu Y, Pei Z, Huo F, Liang X, Wang Y, Wang Q, Xie W, Li Y, Shi M, Bian H, Zhu P, Chen ZN.
Signal Transduct Target Ther. 2021-09-25; 6 (1)
Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion.
Fumagalli V, Ravà M, Marotta D, Di Lucia P, Laura C, Sala E, Grillo M, Bono E, Giustini L, Perucchini C, Mainetti M, Sessa A, Garcia-Manteiga JM, Donnici L, Manganaro L, Delbue S, Broccoli V, De Francesco R, D'Adamo P, Kuka M, Guidotti LG, Iannacone M.
Sci Immunol. 2022-01-28; 7 (67)
The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory.
Ndeupen S, Qin Z, Jacobsen S, Estanbouli H, Bouteau A, Igyártó BZ.
bioRxiv. 2021-07-23;
Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2.
Sun S, Gu H, Cao L, Chen Q, Ye Q, Yang G, Li RT, Fan H, Deng YQ, Song X, Qi Y, Li M, Lan J, Feng R, Guo Y, Zhu N, Qin S, Wang L, Zhang YF, Zhou C, Zhao L, Chen Y, Shen M, Cui Y, Yang X, Wang X, Tan W, Wang H, Wang X, Qin CF.
Nat Commun. 2021-09-27; 12 (1)
Gene expression variability across cells and species shapes innate immunity.
Hagai T, Chen X, Miragaia RJ, Rostom R, Gomes T, Kunowska N, Henriksson J, Park JE, Proserpio V, Donati G, Bossini-Castillo L, Vieira Braga FA, Naamati G, Fletcher J, Stephenson E, Vegh P, Trynka G, Kondova I, Dennis M, Haniffa M, Nourmohammad A, Lässig M, Teichmann SA.
Nature. 2018-10-24; 563 (7730)
SARS-CoV-2 infection in the mouse olfactory system.
Ye Q, Zhou J, He Q, Li RT, Yang G, Zhang Y, Wu SJ, Chen Q, Shi JH, Zhang RR, Zhu HM, Qiu HY, Zhang T, Deng YQ, Li XF, Liu JF, Xu P, Yang X, Qin CF.
Cell Discov. 2021-07-06; 7 (1)
Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model.
Yang T, Poenisch M, Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Araúzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M, Sharma AD.
J Hepatol. 2021-08-25; 75 (6)
Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Peng L, Hu Y, Mankowski MC, Ren P, Chen RE, Wei J, Zhao M, Li T, Tripler T, Ye L, Chow RD, Fang Z, Wu C, Dong MB, Cook M, Wang G, Clark P, Nelson B, Klein D, Sutton R, Diamond MS, Wilen CB, Xiong Y, Chen S.
bioRxiv. 2021-12-24;
Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 in lung epithelium.
Schuler BA, Habermann AC, Plosa EJ, Taylor CJ, Jetter C, Negretti NM, Kapp ME, Benjamin JT, Gulleman P, Nichols DS, Braunstein LZ, Hackett A, Koval M, Guttentag SH, Blackwell TS, Webber SA, Banovich NE, Vanderbilt COVID-19 Consortium Cohort, Human Cell Atlas Biological Network, Kropski JA, Sucre JM.
J Clin Invest. 2021-01-01; 131 (1)
Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis.
Musiu C, Caligola S, Fiore A, Lamolinara A, Frusteri C, Del Pizzo FD, De Sanctis F, Canè S, Adamo A, Hofer F, Barouni RM, Grilli A, Zilio S, Serafini P, Tacconelli E, Donadello K, Gottin L, Polati E, Girelli D, Polidoro I, Iezzi PA, Angelucci D, Capece A, Chen Y, Shi ZL, Murray PJ, Chilosi M, Amit I, Bicciato S, Iezzi M, Bronte V, Ugel S.
Cell Death Differ. 2021-09-13;
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Guo Q, Zhao Y, Li J, Liu J, Yang X, Guo X, Kuang M, Xia H, Zhang Z, Cao L, Luo Y, Bao L, Wang X, Wei X, Deng W, Wang N, Chen L, Chen J, Zhu H, Gao R, Qin C, Wang X, You F.
Cell Host Microbe. 2020-12-26; 29 (2)
Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2-induced systemic toxicity.
Li S, Ma F, Yokota T, Garcia G, Palermo A, Wang Y, Farrell C, Wang YC, Wu R, Zhou Z, Pan C, Morselli M, Teitell MA, Ryazantsev S, Fishbein GA, Hoeve JT, Arboleda VA, Bloom J, Dillon B, Pellegrini M, Lusis AJ, Graeber TG, Arumugaswami V, Deb A.
JCI Insight. 2021-01-25; 6 (2)
Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts.
Chen W, Wang X, Wei G, Huang Y, Shi Y, Li D, Qiu S, Zhou B, Cao J, Chen M, Qin P, Jin W, Ni T.
Front Genet. 2020-08-11; 11
CCR2 Signaling Restricts SARS-CoV-2 Infection.
Vanderheiden A, Thomas J, Soung AL, Davis-Gardner ME, Floyd K, Jin F, Cowan DA, Pellegrini K, Shi PY, Grakoui A, Klein RS, Bosinger SE, Kohlmeier JE, Menachery VD, Suthar MS.
mBio. 2021-11-09; 12 (6)