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HRA000144
   HRA000144.xlsx
Title:
Genomic variations of multi-grade esophageal squamous dysplasia
Release date:
2020-06-05
Description:
The majority of esophageal squamous dysplasia (ESD) are growing slowly, while a subset can undergo recurrence rapidly and progress with lethal consequences even after proper treatment. In the present study, we performed whole-exome sequencing on 105 clinical samples from 80 tumor-free ESD patients. Those genomic variations largely expanded our understanding in genetics and biology of ESD, which possessed promising significance for improving early diagnosis, reducing overtreatment, and identifying high risk ESD patients.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA002513
Study type:
Disease Study
Disease name:
esophageal basaloid squamous cell carcinoma
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC000084
DAC name:
esophageal squamous dysplasia
Contact person:
Zhan Qimin
Email:
zhanqimin@bjmu.edu.cn
Description:
The majority of esophageal squamous dysplasia (ESD) are growing slowly, while a subset can undergo recurrence rapidly and progress with lethal consequences even after proper treatment. In the present study, we performed whole-exome sequencing on 105 clinical samples from 80 tumor-free ESD patients. Those genomic variations largely expanded our understanding in genetics and biology of ESD, which possessed promising significance for improving early diagnosis, reducing overtreatment, and identifying high risk ESD patients.
Individuals & samples
Files
Request Data
Submitter:   Zhan Qimin / zhanqimin@bjmu.edu.cn
Organization:   Peking University Cancer Hospital & Institute
Submission date:   2020-04-10
Requests:   2