Single cell analysis reveals onset of multiple progression associated transcriptomic remodellings in prostate cancer
Release date:
2020-10-21
Description:
Prostate cancer shows remarkable clinical heterogeneity, which strongly manifests at the genomic level. By contrast, the transcriptomic heterogeneity of prostate tumors is poorly understood. We profiled the transcriptomes of 36,424 single-cells from 13 prostate tumors and identified lineage specific epithelial cells underlying disease aggressiveness. The tumor microenvironment showed activation of multiple progression-associated transcriptomic programs.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
The Data Access Committee for the single-cell data of transcriptomes of 36,424 single-cells from 13 prostate tumors collected in Shanghai Changhai Hospital.
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HRA000312.xlsx