RNA-seq of tissue and blood samples from thoracic aortic aneurysm and dissection
Release date:
2020-11-05
Description:
Thoracic aortic tissue was obtained from 8 TAAD human patients undergoing thoracic aneurysm repair surgery. As a control, thoracic aortic tissue from 6 donors with cardiomyopathy undergoing cardiac transplantation was also collected. These tissue samples were subjected to bulk RNA-seq. In addition, to examine the transcriptomic characteristics of macrophages/monocytes in TAAD patients, thoracic aortic tissue and peripheral blood from four TAAD patients were collected. CD11b+ macrophages/monocytes were sorted with antibody-bound magnetic beads from tissue and PBMCs. CD11b+ cells of tissue, CD11b- cells of tissue and CD11b+ PBMCs were subjected to bulk RNA-seq.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
Organization: Fuwai Hospital, Chinese Academy of Medical Sciences
Submission date: 2020-10-21
Requests: -
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