HRA000426
Title:
RNA-seq of tissue and blood samples from thoracic aortic aneurysm and dissection
Release date:
2020-11-05
Description:
Thoracic aortic tissue was obtained from 8 TAAD human patients undergoing thoracic aneurysm repair surgery. As a control, thoracic aortic tissue from 6 donors with cardiomyopathy undergoing cardiac transplantation was also collected. These tissue samples were subjected to bulk RNA-seq. In addition, to examine the transcriptomic characteristics of macrophages/monocytes in TAAD patients, thoracic aortic tissue and peripheral blood from four TAAD patients were collected. CD11b+ macrophages/monocytes were sorted with antibody-bound magnetic beads from tissue and PBMCs. CD11b+ cells of tissue, CD11b- cells of tissue and CD11b+ PBMCs were subjected to bulk RNA-seq.
Data Accessibility:   
Controlled access Request Data
BioProject:
Study type:
Disease Study
Disease name:
thoracic aortic aneurysm
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
DAC name:
ZhouLabDAC
Contact person:
Zhou Zhou
Email:
zhouzhoufuwai@126.com
Description:
Data Access Committee (DAC) of Zhou Lab
Individuals & samples
Submitter:   Zhou Zhou / zhouzhoufuwai@126.com
Organization:   Fuwai Hospital, Chinese Academy of Medical Sciences
Submission date:   2020-10-21
Requests:   -