e.g., HRA000087; HRA000150
HRA000668
Title:
APOE triggers cellular senescence via disturbing nuclear envelope homeostasis
Release date:
2021-02-18
Description:
Apolipoprotein E (APOE) is one of the main cholesterol transporters involved in the maintenance of cholesterol metabolism and is closely related to human lifespan. However, it remains largely unknown how APOE regulates human stem cell senescence.
Data Accessibility:   
Open access
BioProject:
Study type:
Cell line related study
Dataset Download
MetaData:
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Individuals & samples
Individual Accession
Individual Name
Gender
Sample Accession
Sample Name
Sample Description
Individual Accession
Individual Name
Gender
Sample Accession
Sample Name
Sample Description
HRI095731human embryonic stem cells (hESCs)maleHRS145315CNV_ESC_APOE_KOAPOE KO hESCs in WGS
HRI095731human embryonic stem cells (hESCs)maleHRS145316CNV_ESC_WTWT hESCs in WGS
HRI095732human mesenchymal stem cells (hMSCs)maleHRS145309RNAseq_P3_APOE_KOAPOE KO hMSCs at early passage in RNAseq
HRI095732human mesenchymal stem cells (hMSCs)maleHRS145310RNAseq_P3_WTWT hMSCs at early passage in RNAseq
HRI095732human mesenchymal stem cells (hMSCs)maleHRS145311Dam-Emerin_APOE_KO_P3Dam-EMD of APOE KO hMSCs at early passage in DamID-seq
HRI095732human mesenchymal stem cells (hMSCs)maleHRS145312Dam-Emerin_WT_P3Dam-EMD of WT hMSCs at early passage in DamID-seq
HRI095732human mesenchymal stem cells (hMSCs)maleHRS145313DamOnly_APOE_KO_P3DamOnly of APOE KO hMSCs at early passage in DamID-seq
HRI095732human mesenchymal stem cells (hMSCs)maleHRS145314DamOnly_WT_P3DamOnly of WT hMSCs at early passage in DamID-seq
HRI095732human mesenchymal stem cells (hMSCs)maleHRS145317CNV_MSC_APOE_KOAPOE KO hMSCs in WGS
HRI095732human mesenchymal stem cells (hMSCs)maleHRS145318CNV_MSC_WTWT hMSCs in WGS
Showing 1 to 10 of 12 rows rows per page
Files
Run accession
Files
Experiment
Experiment title
Platform
Sample
Run accession
Files
Experiment
Experiment title
Platform
Sample
HRR204617HRR204617_f1.fq.gz (0.88 GB)HRX166485RNAseq_P3_APOE_KO_rep1Illumina HiSeq X TenHRS145309 (SAMC1584236)
HRR204617HRR204617_r2.fq.gz (0.91 GB)HRX166485RNAseq_P3_APOE_KO_rep1Illumina HiSeq X TenHRS145309 (SAMC1584236)
HRR204618HRR204618_f1.fq.gz (0.95 GB)HRX166486RNAseq_P3_APOE_KO_rep2Illumina HiSeq X TenHRS145309 (SAMC1584236)
HRR204618HRR204618_r2.fq.gz (0.98 GB)HRX166486RNAseq_P3_APOE_KO_rep2Illumina HiSeq X TenHRS145309 (SAMC1584236)
HRR204619HRR204619_f1.fq.gz (0.89 GB)HRX166487RNAseq_P3_WT_rep1Illumina HiSeq X TenHRS145310 (SAMC1584238)
HRR204619HRR204619_r2.fq.gz (0.91 GB)HRX166487RNAseq_P3_WT_rep1Illumina HiSeq X TenHRS145310 (SAMC1584238)
HRR204620HRR204620_f1.fq.gz (0.96 GB)HRX166488RNAseq_P3_WT_rep2Illumina HiSeq X TenHRS145310 (SAMC1584238)
HRR204620HRR204620_r2.fq.gz (0.98 GB)HRX166488RNAseq_P3_WT_rep2Illumina HiSeq X TenHRS145310 (SAMC1584238)
HRR204621HRR204621_f1.fq.gz (2.92 GB)HRX166489Dam-Emerin_APOE_KO_P3_rep1Illumina HiSeq X TenHRS145311 (SAMC1584242)
HRR204621HRR204621_r2.fq.gz (2.95 GB)HRX166489Dam-Emerin_APOE_KO_P3_rep1Illumina HiSeq X TenHRS145311 (SAMC1584242)
Showing 1 to 10 of 56 rows rows per page
Submitter:   Liu Guanghui / ghliu@ioz.ac.cn
Organization:   Institute of Zoology, Chinese Academy of Sciences
Submission date:   2021-02-18