Changes of single-cell transcriptome during adult liver transplantation
Release date:
2021-03-26
Description:
We used scRNA-seq to obtain the first unbiased and comprehensive liver transplant cell atlas by collecting liver tissue samples pre-procurement (PP), at the end of preservation (EP) and 2 h post-reperfusion (PR). This atlas annotated different cell subgroups, revealed their changes in the transcriptome and illustrated the interactions between different cell subpopulations during liver transplantation. This research will serve as an important resource to further understand the cellular and molecular mechanism of graft IRI during liver transplantation.
Organization: The First Affiliated Hospital, Sun Yat-sen University
Submission date: 2021-03-23
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