GWAS analysis of individual gray metter covariance in First-episode schizophrinia patients exome-sequencing
Release date:
2021-05-10
Description:
Reliable mapping of individual differences from a systems-perspective is a critical first step towards precision medicine for complex disorders such as schizophrenia. Most current studies construct structural covariance networks at the group-level that are not feasible for individual inference. We introduced a new method to build individual differential structural covariance network (IDSCN) using regional gray-matter volume, and we conducted GWAS analysis to identify the genetic basis of the individual covariance links
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HRA000812.xlsx