Single-cell chromatin accessibility landscapes of colorectal adenomas and cancer
Release date:
2024-02-29
Description:
To systematically address the question how epigenetic state changes in epithelial cells across adjacent normal colon, colorectal adenomas and colorectal cancer, we performed snATAC-seq (single-nucleus Assay for Transposase Accessible Chromatin using sequencing) on 21,311 cells from 34 adjacent normal colon tissues, 10 colorectal adenoma tissues and 45 colorectal cancer tissues of 34 donors.
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