Ribosomal DNA methylation patterns of plasma cell-free DNA for hepatocellular carcinoma (HCC) patients versus liver cirrhosis patients
Release date:
2022-01-13
Description:
Hepatocellular carcinoma (HCC) patients (n = 12) were recruited from the Fifth Medical Center of Chinese PLA General Hospital. Patients with liver cirrhosis (n=7) were also recruited as controls. Cell-free DNA were extracted from blood and then performed with WGBS. Ribosomal DNA methylation changes achieved 96% AUC in distinguishing HCC and cirrhosis
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