HRA001045
Title:
Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions
Release date:
2021-07-19
Description:
Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape of clinically-relevant kinase fusions in Chinese lung cancer and to explore rare kinase rearrangements; thus, providing valuable evidence for therapeutic decision making. We performed genomic profiling of 425 cancer-relevant genes from tumor/plasma biopsies from a total of 17,442 Chinese lung cancer patients using next generation sequencing (NGS).
Data Accessibility:   
Controlled access Request Data
BioProject:
Study type:
Disease Study
Disease name:
lung cancer
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
DAC name:
lung cancer_RTK fusion
Contact person:
Zhang Xian
Email:
xian.zhang@geneseeq.com
Description:
3 members, responsible for the data management
Individuals & samples
Submitter:   Lin Nong / 2101079@zju.edu.cn
Organization:   The Second Affiliated Hospital of Zhejiang University School of Medicine
Submission date:   2021-07-14
Requests:   -