Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions
Release date:
2021-07-19
Description:
Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape of clinically-relevant kinase fusions in Chinese lung cancer and to explore rare kinase rearrangements; thus, providing valuable evidence for therapeutic decision making. We performed genomic profiling of 425 cancer-relevant genes from tumor/plasma biopsies from a total of 17,442 Chinese lung cancer patients using next generation sequencing (NGS).
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
Organization: The Second Affiliated Hospital of Zhejiang University School of Medicine
Submission date: 2021-07-14
Requests: -
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