The rested dataset for single-cell RNA sequencing reveals regulatory mechanism for trophoblast cell-fate divergence in human peri-implantation conceptuses
Release date:
2021-09-16
Description:
We obtained human peri-implantation embryos through blastocyst to early post -implantation stages using an in vitro coculture system, and profiled transcriptome of individual trophoblast cells collected from these embryos. By systematic analysis methods, we revealed the genetic networks regulating peri-implantation trophoblast development.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
Although many efforts were spent to treat infertility, the pathogenesis and effective treatments were still absent. For exploring the mechanism of inferility, we performed human oocyte or embyro on RNA-seq. Gene expression profile were detected using single-cell RNA sequencing.
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HRA001282.xlsx