Ascites and Serial Plasma Circulating Tumor DNA for Predicting the Effectiveness of Hyperthermic Intraperitoneal Chemotherapy in Patients with Peritoneal Carcinomatosis
Release date:
2021-10-29
Description:
In this observational study, 19 patients with PC were enrolled. Serial plasma ctDNA was analyzed by next-generation sequencing (NGS). The molecular tumor burden index (mTBI) was used to detect ctDNA, and concurrent changes in the dominant clone variant allele frequency (VAF) and common tumor markers, were used as controls. The correlation between ascites and plasma ctDNA co-mutated genes was expressed by the VAF.
Organization: The Affiliated Changzhou No.2 People’s Hospital of Nanjing Medical University
Submission date: 2021-10-29
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