Whole exome sequencing of 1030 patients with premature ovarian insufficiency
Release date:
2022-10-23
Description:
Premature ovarian insufficiency (POI) is a major cause of female infertility due to early loss of ovarian function. Yet a large proportion of POI cases are idiopathic, with multiple lines of evidence supporting a genetic basis for pathogenesis. Here, we performed whole-exome sequencing in a large POI cohort of 1,030 patients aimed to provide a detailed characterization of its genetic landscape.
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HRA003245.xlsx