Synovium is an important component of the joint and the major site of inflammation in arthritic diseases, which plays a critical role in the pathogenesis of these conditions. The study of gene expression regulation mechanism in synovial tissue is of great importance to elucidate the genetic mechanism of arthritic diseases. However, the regulatory landscape of gene expression in synovial tissue remains poorly understood, due to the absence of large-scale resources. Here, we aimed to fill this knowledge gap by integrating genomics with transcriptomics and chromatin accessibility features of human synovium from up to 202 osteoarthritis patients.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
You need to install the Aspera Connect plugin before uploading your files. If you dont have Aspera Connect plugin installed in your computer, please Download Aspera Connectand install it first.
[path/to/ascp]: Microsoft Windows: C:\Program Files\Aspera\Aspera Connect\bin\ascp.exe or
c:\users\[username]\AppData\Local\Programs\Aspera\Aspera Connect\bin\ascp.exe
Mac OS X: /Applications/Aspera/Connect.app/Contents/Resources/ascp (for admin's installation) or
/Users/[username]/Applications/Aspera/Connect.app/Contents/Resources/ascp (for non-admin's installation)
Linux: /opt/aspera/bin/ascp or
/home/[username]/aspera/connect/bin/ascp
[path/to/key/file] must be an absolute path, e.g.: /home/keys/aspera.openssh
[path/to/folder/containing/files] needs to specify the local folder that contains all the files to upload.
HRA004624.xlsx