ITDFinder: Detecting and quantifying FLT3-ITD based on clustering and random forest algorithm
Release date:
2023-11-30
Description:
We developed a software called ITDFinder that uses the clustering of candidate mutant reads, which encompass soft-clip, hard-clip and insertion in cigar string ,to ensure qualitative accuracy. Additionally, random forest regression model was performed to correct the quantitative result. This ensures the qualitative and quantitative precision of FLT3-ITD detection as demanded in clinical practice.
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HRA006132.xlsx