Transcriptomics of neoadjuvant therapy for gastric cancer
Release date:
2024-10-17
Description:
Here, we used Bulk RNA-Seq to analyze pre- and post-neoadjuvant paired samples from 48 patients with locally advanced gastric cancer, including 25 neoadjuvant immunochemotherapy and 23 neoadjuvant chemotherapy. Our study systematically analyzed the effects of different neoadjuvant treatment regimens on the tumor immune microenvironment of gastric cancer and the dynamic changes before and after treatment, and elucidated the immunological mechanism by which neoadjuvant immunochemotherapy is superior to chemotherapy alone.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
Department of Gastroenterology & Chongqing Key Laboratory of Digestive Malignancies, Daping Hospital, Army Medical University (Third Military Medical University), 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, P. R. China.
You need to install the Aspera Connect plugin before uploading your files. If you dont have Aspera Connect plugin installed in your computer, please Download Aspera Connectand install it first.
[path/to/ascp]: Microsoft Windows: C:\Program Files\Aspera\Aspera Connect\bin\ascp.exe or
c:\users\[username]\AppData\Local\Programs\Aspera\Aspera Connect\bin\ascp.exe
Mac OS X: /Applications/Aspera/Connect.app/Contents/Resources/ascp (for admin's installation) or
/Users/[username]/Applications/Aspera/Connect.app/Contents/Resources/ascp (for non-admin's installation)
Linux: /opt/aspera/bin/ascp or
/home/[username]/aspera/connect/bin/ascp
[path/to/key/file] must be an absolute path, e.g.: /home/keys/aspera.openssh
[path/to/folder/containing/files] needs to specify the local folder that contains all the files to upload.
HRA006247.xlsx